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Children with a devastating genetic disorder characterized by severe motor disability and developmental delay have experienced sometimes dramatic improvements in a gene therapy trial launched at UCSF Benioff Children’s Hospitals.
Scientists at UCSF have shown that gene-edited cellular therapeutics can be used to successfully treat cardiovascular and pulmonary diseases in mice.
Taking a page from computer engineers, biologists are trying their hands at programming cells – by building DNA circuits to guide their protein-making machinery and behavior.
UCSF Benioff Children’s Hospitals is poised to lead the UC System and the state in pediatric medicine, according to its two senior leaders, who held a virtual fireside chat to discuss the past,
Plenty of probiotic yogurts, pickles and kombuchas claim to boost our digestive health with armies of microbes, but some scientists have more ambitious therapeutic plans for the “bugs” that colonize us. They hope to leverage these microbes as living therapeutics for a range of health conditions, including ulcerative colitis, multiple sclerosis, eczema and asthma.
Pioneer, giant, visionary – these are just a few of the words that describe John Severinghaus and his work to advance anesthesia and medicine.
Every year, 10,000 liters of liquid helium are used by just two imaging facilities housed at UCSF’s Mission Bay campus managed by the UCSF Schools of Pharmacy and Medicine—enough to fill 625,000 birthday balloons.
Researchers at UC San Francisco have found that extreme caloric restriction diets alter the microbiome in ways that could help with weight loss but might also result in an increased population of Clostridioides difficile, a pathogenic bacterium that can lead to severe diarrhea and colitis.
At the recent June Precision Medicine World Conference, scientists and health experts from academia, government, and industry discussed how a precision medicine approached has helped to curb the pandemic and how lessons learned can be used to build resilience against future threats.
There is a chance that in every lecture, laboratory, Zoom meeting, town hall audience or shuttle bus ride, someone around you is battling a mental health challenge or knows someone who is struggling.
Individuals with HIV are more than twice as likely to die from sudden cardiac death (SCD) compared to the general population, and more likely to have hearts compromised by fibrosis, a factor that may play a role in increasing their susceptibility to SCD, according to new findings from a UCSF study.
This long-delayed treatment milestone might not have happened at all without seminal accomplishments by UCSF chemist Kevan Shokat, who succeeded in revitalizing a holy-grail-like quest after almost all others had given up.
T cells – immune cells that patrol our bodies in search of trouble – have become a central focus for UC San Francisco scientists working on living cell therapies, an approach that views cells
After more than four decades at UCSF, B. Joseph Guglielmo, PharmD, dean of the UCSF School of Pharmacy, who has led for nearly 10 years what is widely regarded as the best pharmacy school in the nation, has announced that he will retire December 31, 2021.
The B.1.1.7 coronavirus variant—also known as Alpha—may be more infectious because it contains mutations that make it better adapted to foil the innate immune system, at least for long enough to allow the virus to replicate and potentially find new hosts, according to a new study.
After their hard work, dedication and resilience during a year of challenges, students across UCSF have a lot to celebrate as they earn their degrees. Join us in celebrating our graduates.
UCSF Benioff Children’s Hospitals have been recognized among the nation’s best pediatric medical centers in all 10 specialties assessed in U.S. News & World Report’s annual survey of Best Children’s Hospitals for 2021-2022.
For older adults, participating in social activities can protect against physical and mental signs of aging, but it may also pose risks, especially for women. A new analysis of national data led by
UCSF is launching a new initiative to propel the development of living therapeutics – a category of treatments broadly defined as human and microbial living cells that are selected, modified, or engineered to treat or cure disease – and bring them quickly to patients.
UCSF alum Michael Drake, MD ’75, weighs in on leadership and what’s ahead for the University of California.
UCSF School of Nursing alum Quinn Grundy, PhD ’15, RN, shines a light on how sales reps from pharmaceutical and other health care companies skirt scrutiny, and get their products used in hospitals and doctors’ offices, by forging relationships with nurses.