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Alzheimer’s disease is characterized by a host of recognizable cognitive symptoms, but many non-cognitive symptoms like changes in sleep, anxiety and depression can be early signs of the disease.
UCSF scientists discover how cancer cells hijack the protein factory of the cell to churn out MYC protein, the driver of 70% of all cancers.
Nearly 50 UCSF researchers have been named to Clarivate’s list of most influential scientists for 2024.
UCSF researchers develop customizable SNIPR sensors that activate engineered cells only near tumors, promising precise cancer therapies with minimal side effects.
With the help of up to $30M in funding, researchers led by UCSF’s James Fraser, PhD, will use AI to map drug “anti-targets,” aiming to speed up drug development and reduce costs.
Breast cancer is the second leading cause of cancer deaths in the U.S. and worldwide, pointing to the continuing need to improve treatment strategies and therapies that better patient survival and
Powerful electron microscopy and 3D imaging leads scientists to a new discovery showing how the TGF-Beta signaling protein is able to move much more freely than previously thought.
Aashish Manglik delivered the 29th annual Byers Award Lecture titled “Signal Reception: Cracking Codes in Cellular Communication.”
Added sugar in diet can speed up epigenetic aging, while a sustained, healthy diet with can slow it down and possibly reverse biological aging.
A newly discovered hormone explains why females can maintain bone density during lactation, when calcium is stripped away to make milk. This discovery could one day have applications to treating fractures, osteoporosis, and other bone diseases.
Multiciliated cells, cells with hundreds of hair-like structures that move called cilia, keep things like mucus in the lungs and cerebrospinal fluid in the brain flowing in the right direction.
A new drug candidate permanently modifies a wily cancer-causing mutation, paving the way for making pancreatic cancer treatable, or perhaps even curable.
Delivering medicine through amniotic fluid is as effective as delivering it to the fetal brain via cerebrospinal fluid to treat serious disordrs such as Angelman syndrome.
UCSF scientists found a way to predict Alzheimer’s disease up to seven years before symptoms appear by analyzing patient records with machine learning. Conditions that most influenced prediction of Alzheimer’s were high cholesterol and, for women, osteoporosis.
Thirty-two UCSF scientists are among the most influential individuals in their respective fields, according to the most recent analysis of research citations by the science and intellectual property company, Clarivate.
UCSF researchers are working across disease specialties. Diabetes researchers are looking at how oncologists use CAR T-cell therapy to reprogram a person’s immune system to attack cancer cells, for example. They hope to similarly reprogram the immune system to fight diabetes.
Engineered immune cells. Supercharged scans. Drug implants. Gene manipulators. Blood biopsies. Read how these breakthroughs are transforming cancer care.
Two UCSF scientists – James Gardner, MD, PhD, and Rebeca de Pavia Fróes Rocha, PhD – have received Pew awards for their work in immunology as part of a program that supports promising early-career investigators.
Oncology specialists from around the globe will gather for the American Society of Clinical Oncology (ASCO) Annual Meeting to discuss the latest cancer therapies, technologies, research and education.
UCSF researchers discover how gabapentin interacts with calcium channels, opening doors for more effective treatments in epilepsy and Lupus by influencing channel biogenesis.
A traditional African psychedelic plant medicine called ibogaine is the blueprint for two new drug candidates that could treat addiction and depression.
In a first, UCSF scientists created a molecular-level, 3D picture of how an odor molecule activates a human odorant receptor.
Faranak Fattahi’s lab is a national leader in growing stem cells to model peripheral nerves, focusing on gastrointestinal diseases.
Emily Goldberg's lab studies what happens during aging to a particular set of immune cells: those embedded in fat tissue. She hypothesizes that changes to these cells during aging could be key to age-related inflammation.
Angela Phillips, PhD, leads research that could help predict future viruses like COVID and the antibodies we might use to treat them.
Leanne Jones, PhD, is at the forefront of studying how stem cells are influenced by their surrounding environment and directed to differentiate into one type of cell or another – research that’s critical for stem cell therapies to be successful.
Because proteins can adapt to extremes, Margaux Pinney, PhD, believes they can show how living organisms might adapt to climate change.
Vissers’ work on RNA tags helped found the field of epitranscriptomics, the study of how chemical marks on RNA, rather than their sequence alone, dictate the function of the molecules.
