Killing Cancer Through the Immune System
Researchers are harnessing the power of the body's natural defenses to fight deadly cancers, and the treatment appears to be powerful, effective and long-lasting.
University of California San Francisco
Give to UCSFResearchers are harnessing the power of the body's natural defenses to fight deadly cancers, and the treatment appears to be powerful, effective and long-lasting.
Experts across UCSF weigh in on what some of 2014's top trends are in research and patient care.
Research led by scientists at the UCSF-affiliated Gladstone Institutes has identified the precise chain of molecular events in the human body that drives the death of most of the immune system’s CD4 T cells as an HIV infection leads to AIDS. Further, they have identified an existing anti-inflammatory drug that in laboratory tests blocks the death of these cells.
Children’s risk for developing allergies and asthma is reduced when they are exposed in early infancy to a dog in the household, and now researchers have discovered a reason why.
UCSF researchers received six of 78 awards announced this week by the National Institutes of Health for innovative, high-risk, high-reward research.
A new link between meal times and daily changes in the immune system has been identified by UCSF researchers, and has led them to question assumptions about the roles of specific immune cells in infection and allergy.
Scientists from UCSF have identified a new way to manipulate the immune system that may keep it from attacking the body’s own molecules in autoimmune diseases such as type 1 diabetes, rheumatoid arthritis and multiple sclerosis.
A protein at the center of Parkinson’s disease research now also has been found to play a key role in causing the destruction of bacteria that cause tuberculosis.
Adenoviruses commonly infect humans, causing colds, flu-like symptoms and sometimes even death, but now UCSF researchers have discovered that a new species of adenovirus can spread from primate to primate, and potentially from monkey to human.
Raising hopes for cell-based therapies, UCSF researchers have created the first functioning human thymus tissue from embryonic stem cells in the laboratory.
DNA sequences obtained from a handful of patients with multiple sclerosis at the UCSF Medical Center have revealed the existence of an “immune exchange” that allows the disease-causing cells to move in and out of the brain.
As mothers have always known, a good night’s sleep is crucial to good health — and now a new study led by a Robert Wood Johnson Foundation Health & Society Scholar at UCSF and UC Berkeley shows that poor sleep can reduce the effectiveness of vaccines.
<p>Yervoy, a new cancer drug that has been approved for the treatment of late-stage melanoma – and that is being used to treat other cancers in ongoing clinical trials – is based on a strategy for boosting the immune response developed and tested by scientists from UCSF and UC Berkeley.</p>
Men and women had starkly different immune system responses to chronic post-traumatic stress disorder, with men showing no response and women showing a strong response, in two studies by researchers at the San Francisco VA Medical Center and the University of California, San Francisco.
<em>The Lancet</em> launched a special series on malaria elimination Oct. 29, led by the Global Health Group (GHG), a part of UCSF Global Health Sciences. The series included work by 36 authors worldwide, with guidance and support provided by a GHG-convened global advisory group of malaria experts, known as the Malaria Elimination Group.
The heavy burden of hunger in the United States helps explain why the poor are at higher risk for obesity, high blood pressure and diabetes, according to an editorial in the July 1 <i>New England Journal of Medicine</i> co-authored by two UCSF faculty members.
An international study published in the March 25 <em>New England Journal of Medicine</em> showed what researchers call a clinical breakthrough in one of the greatest unmet needs for patients with advanced liver disease.
Narcolepsy, a sleep disorder that can cause sufferers to suddenly lose muscle tone and start dreaming, is an autoimmune disease, a team led by UCSF and Stanford scientists finds.