University of California San Francisco
Give to UCSF
Displaying 2671 - 2700 of 2966
-
-
UCSF Study Shows Greater Impact of Chemotherapy on Fertility
UCSF researchers say their analysis of the age-specific, long-term effects of chemotherapy on women provides new insights that will help patients and clinicians make more informed decisions about future reproductive options, such as egg harvesting.
-
Gladstone Scientist Identifies Gene that Exacerbates Risk Factors for Heart Disease and Diabetes
A scientist at the UCSF-affiliated Gladstone Institutes has discovered how a gene contributes to a suite of health problems sweeping across America, offering new insight into how to combat these potentially fatal conditions.
-
New Asthma Risk Gene Emerges from Study of Diverse Populations
<p>Asthma risk genes, inluding one in African Americans, have been identified in a new analysis of several large genome-wide studies of ethnically diverse populations.</p>
-
Major Genetic Study of Multiple Sclerosis Reveals DNA Hot Spots of Disease Susceptibility
<p>A consortium of scientists is reporting that genetic secrets of multiple sclerosis may be buried in 50 “hot spots” in the human genome, a finding that will guide future efforts to assess an individual’s risk of susceptibility and may help develop new drugs for treating this complex disease.</p>
-
Sleep Apnea
-
Common Sleep Problem Raises Dementia Risk
-
Sleep Apnea May Raise Dementia Risk in Women
-
Study Finds High Levels of Flame Retardant Chemicals in California Pregnant Women
A UCSF-led pilot study in San Francisco has found the highest levels ever reported among pregnant women worldwide of banned chemicals used in flame retardants, a likely result, they believe, of California’s strict flammability regulations.
-
Sleep Apnea-Dementia Link Revealed in New Study
-
Sleep Apnea Linked to Dementia in Older Women
-
Sleep Apnea Linked to Increased Risk of Dementia in Elderly Women
Elderly women who suffer from sleep apnea -- characterized by disrupted breathing and sleep and a reduction in the intake of oxygen -- are about twice as likely to develop dementia in the next five years as those without the condition, according to a multi-center study led by researchers from the University of California, San Francisco.
-
Treatment of Sleep-Disordered Breathing May Prevent Dementia
-
What Steers Vampires to Blood
Scientists have known for years that when vampire bats tear through an animal’s skin with their razor-sharp teeth, their noses guide them to the best spots – where a precise bite will strike a vein and spill forth nourishing blood. But nobody knew exactly how bats knew where to bite – until now.
-
UCSF and Kaiser Permanente Complete Massive Genotyping Project
The completion of a massive genotyping on a large and diverse population marks an unprecedented milestone in population-based genetics research and offers a unique and powerful resource to help answer research questions about aging, health and disease.
-
Over Half of Alzheimer's Cases May Be Preventable, Say Researchers
Over half of all Alzheimer’s disease cases could potentially be prevented through lifestyle changes and treatment or prevention of chronic medical conditions, according to a study led by Deborah Barnes, PhD, a mental health researcher at the San Francisco VA Medical Center.
-
Traumatic Brain Injury More Than Doubles Dementia Risk
Patients diagnosed with traumatic brain injury (TBI) had over twice the risk of developing dementia within seven years after diagnosis compared to those without TBI, in a study of more than 280,000 older veterans conducted by researchers at the San Francisco VA Medical Center and UCSF.
-
Brain Research at UCSF Aims to Help Distracted Remember
<p>UCSF cognitive neuroscientist Adam Gazzaley has used functional brain imaging and EEG studies to discover that older adults fare worse than younger adults at remembering following distractions. He hopes to improve their performance with cognitive training, using a newly developed video game.</p>
-
NIH Director Says Timing Right to Reengineer Translational Science
<p>Francis Collins, director of the National Institutes of Health (NIH), describes the scientific goals and functions of the National Center for Advancing Translational Sciences (NCATS), a proposed new entity of the NIH that will strive to reengineer the process of developing drugs, diagnostics, and devices. </p>
-
NIH Director Tours QB3 at Mission Bay to View Translational Science in Action
<p>As part of his push for the National Institutes of Health to focus more on translational medicine, Director Francis Collins recently toured one of UCSF’s world-class centers of innovation, the California Institute for Quantitative Biosciences (QB3) at Mission Bay.</p>
-
UCSF Team Describes Genetic Basis of Rare Human Diseases
Researchers at UCSF and in Michigan, North Carolina and Spain have discovered how genetic mutations cause a number of rare human diseases, which include Meckel syndrome, Joubert syndrome and several other disorders.
-
Mapping the Brain with Philip Sabes, PhD
<p>By mapping neurons and neuron circuitry during movement, Sabes’ lab hopes to one day to be able to print this information back into the brain. If feasible, such therapy could offer new hope to stroke victims whose brains are unable to recover on their own.</p>
-
New Life for Damaged Nerves with Hubert Kim, MD, PhD
<p>Each year, scores of soldiers wounded by explosives suffer from debilitating nerve injuries that render their arms and legs useless. Kim’s research, performed at the UCSF-affiliated San Francisco Veterans Affairs hospital, has led to development of artificial nerve grafts to accelerate healing of these injuries.</p>
-
Rethinking Prostate Cancer with Matthew Cooperberg, MD, MPH
<p>In the era of prostate cancer screening, mortality rates have fallen 40 percent. The price of that has been over-diagnosis and over-treatment, something the current health care system cannot sustain. One of the major goals of Cooperberg’s research is to develop better risk assessment tools and instruments that can give the patient and doctor more confidence that the patient’s cancer will not progress.</p>
-
Mining the Human Body with Michael Fischbach, PhD
<p>Having developed an algorithm that discovered a large quantity of drug-producing bacteria in and on humans, Fischbach has turned his lab’s attention to studying their populations and interactions with each other. This, he posits, can greatly influence a person’s overall health and disease.</p>
-
Smarter Drug Delivery with Tejal Desai, PhD
<p>Swallowing pills means medication must face the challenge of surviving the harsh environment of the digestive tract. As a result, people must take larger doses than they need. Using micro and nano-fabrication techniques developed by the computer chip industry, Desai’s lab is creating tiny devices that take multiple drugs directly to where they are needed, using less medication, minimizing side effects and making the process safer for the patient. </p>
-
Window into the Brain with Adam Boxer, MD, PhD
<p>Many researchers are finding that by the time a patient seeks treatment for symptoms of Alzheimer’s disease, it’s often too late for the available drugs to have an effect. Boxer’s lab is studying very precise eye tracking methods to gauge mental fitness and identify cognitive decline decades before the first symptoms appear.</p>
-
Sleep and Pregnancy with Kathryn A. Lee, RN, PhD, FAAN
<p>With years of sleep research under her belt, Lee has recently focused on helping parents — especially new and expecting mothers — get enough sleep. From these studies, Lee has found worrisome correlations between sleep deprivation during pregnancy and increased instances of Cesarean operations and length of labor. By educating families about proper sleep hygiene, she hopes to promote healthier home environments for mothers and babies.</p>
-
Growing New Teeth with Ophir Klein, MD, PhD
<p>By understanding the underlying biological processes that allow teeth to continuously grow in rodents and other mammals, Klein’s research aims to apply those principles to regenerative medicine in humans. Klein predicts that one day patients will be able to replace their own lost teeth with living, biological replicas instead of the prosthetics oral surgeons implant today.</p>
-
Treating Disease Before Birth with Tippi MacKenzie, MD
Stem cell transplantation may hold the promise to treating many diseases before birth such as sickle cell anemia and muscular dystrophy. But first, researchers need to overcome many barriers, including rejection of stem cell transplants by the fetus. MacKenzie’s lab recently discovered that mothers’ T cells are responsible for rejecting the grafts and that this rejection may be avoided by using stem cells from the mother.