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Graduate student Lauren Rodda captured a microscopic mage of a mouse gut, which highlights her work to understand the germinal center, where immune cells compete to be the best at recognizing an invading pathogen.
Researchers at UCSF and the academically affiliated Gladstone Institutes have used a newly developed gene-editing system to find gene mutations that make human immune cells resistant to HIV infection.
UCSF has ranked as one of the top 20 universities in the world, according to the 2017 Best Global Universities rankings released Tuesday by U.S. News & World Report.
Lenore Pereira, a virologist and professor in School of Dentistry’s Department of Cell and Tissue Biology, is in the middle of crucial research to understand how the mosquito-borne Zika virus harms the babies of women infected during pregnancy.
Using a mouse model of multiple sclerosis, UCSF scientists demonstrated that regenerating myelin can both protect neurons from damage and restore lost function.
UCSF scientists have engineered human immune cells that can precisely locate diseased cells anywhere in the body and execute a wide range of customizable responses, including the delivery of drugs or other therapeutic payloads directly to tumors or other unhealthy tissues.
Gut microbes present in some one-month-old infants predict a three-fold higher risk of developing allergic reactions by age two and asthma by age four.
The abundance of a subtype of white blood cells in melanoma tumors can predict whether or not patients will respond to a form of cancer immunotherapy known as checkpoint blockade, according to a new study led by UCSF researchers and physicians.
A new study led by UCSF scientists shows that a bacterium commonly found in the human gut is overrepresented in patients with a rare, often disabling autoimmune disease known as neuromyelitis optica.
Zika virus can infect numerous cell types in the human placenta and amniotic sac, according to researchers at UCSF and UC Berkeley who show in a new paper how the virus travels from a pregnant woman to her fetus.
Using advanced imaging technology that allowed them to spy on interactions among cells in the lymph nodes of living mice, a research team led by UCSF scientists has identified a cell that is a key player in mounting the immune system’s defense against cancer.
A previously unidentifiable type of low-grade inflammation may explain why common anti-inflammatory drugs such as aspirin have shown promise against some types of cancer – even when patients don’t display typical signs of inflammation.
UC San Francisco researchers have shed light on how the immune system of a fetus can run amok, triggering inflammation in the developing intestines that protrude outside of the body through a hole beside the belly button.
With one drug to shut down its progression and another to undo its damage, plus a worldwide effort stalking the origins of multiple sclerosis, MS doesn’t stand a chance.
Renowned UCSF immunologist Jeffrey Bluestone, PhD, has been named president and CEO of the Parker Institute for Cancer Immunotherapy, a national initiative launched with a $250 million grant from The Parker Foundation, established by Silicon Valley entrepreneur Sean Parker.
Scientists at UC San Francisco have been able to directly observe, for the first time, how invasive cancer cells create a beachhead as they migrate to the lung in a mouse model of metastatic cancer.
Research by UCSF scientists has opened up a surprising new avenue for potential therapies to reduce the risk of type 2 diabetes and other metabolic disorders that are associated with chronic tissue inflammation in obesity.
Leading microbiome researchers recently came to UCSF to share the newest insights about how improving our relationship with our bodies’ microbial ecosystems could be the next big breakthrough in treating metabolic disease.
UCSF scientists have created a new class of highly customizable biological sensors that can be used to form “logic gates” inside cells of the immune system, giving these cells the capability to home in on and kill a wide range of cancer cells while preventing them from attacking normal tissue.
The cells that create myelin, a fatty material that insulates nerve fibers in the brain’s white matter, migrate into the developing brain by climbing and swinging on blood vessels, according to new research led by UCSF scientists.
In a bid to end the worst epidemic in modern times, the Foundation for AIDS Research (amfAR) is funding an ambitious effort based in San Francisco to eliminate the human immunodeficiency virus (HIV) from those who are infected.
In the first U.S. safety trial of a new form of immunotherapy for type 1 diabetes, patients experienced no serious adverse reactions after receiving infusions of as many as 2.6 billion cells that had been specially selected to protect the body’s ability to produce insulin.
A wave of specialized immune cells entering the skin in early life may induce tolerance to the hundreds of species of so-called friendly bacteria that live on the surface of the body.
A $10 million gift from The Parker Foundation, founded by Silicon Valley entrepreneur and philanthropist Sean Parker, will establish a new research laboratory within the UCSF Diabetes Center devoted to understanding autoimmunity.
To help stop the spread of antibiotic resistance, UCSF scientists are urging hospitals around the country to stop buying meat from animals that were given antibiotics for growth promotion.
A virus is nature’s efficient little killer. They’re really good at what they do, and we’ve been able to harness their skills to learn about – and potentially improve – human health in several ways.
UCSF researchers have engineered a molecular “on switch” that allows tight control over the actions of T cells, immune system cells that have shown great potential as therapies for cancer.
A rare, deadly form of skin cancer known as desmoplasmic melanoma may possess the highest burden of gene mutations of any cancer, suggesting that immunotherapy may be a promising approach for treatment, according to an international team led by UCSF scientists.
A new study led by a UCSF sleep researcher supports what parents have been saying for centuries: to avoid getting sick, be sure to get enough sleep.
UCSF researchers have discovered that the adaptive immune system plays an active role in guiding the normal development of mammary glands, the only organs that develop predominantly after birth, beginning at puberty.