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UCSF researchers found that 58 percent of women who resided in a nursing home for more than 90 days before breast cancer surgery experienced significant functional decline one year after surgery.
In these patients, chronic tissue inflammation causes an over-active protein to introduce mutations across the genome, some of which eventually lead to cancer.
Use of e-cigarettes every day can nearly double the odds of a heart attack, according to a new analysis of a survey of nearly 70,000 people, led by researchers at UCSF.
Researchers have identified a new strategy for potentially treating a subset of intractable cancers by decoupling the entire RAS / MAP Kinase signaling pathway from external growth signals.
The Greater Bay Area Cancer Registry, which has been at the forefront of cancer data collection throughout the region is moving its headquarters and management to UCSF.
A decades-old medical mystery has been solved by researchers at UCSF and St. Jude Children’s Research Hospital in Tennessee, who have discovered a pair of inherited genetic mutations underlying a familial blood disorder that sometimes leads to leukemia.
UCSF scientists have used a high-throughput CRISPR-based technique to rapidly map the functions of nearly 500 genes in human cells, many of them never before studied in detail.
A comprehensive genetic analysis of metastatic prostate cancer has, for the first time, revealed a number of major ways in which abnormal alterations of the genome propel this aggressive form of the disease.
Follow-up imaging for women with non-metastatic breast cancer varies widely across the country, according to a new study led by researchers at UCSF.
In an achievement that has significant implications for research, medicine, and industry, UCSF scientists have genetically reprogrammed human immune cells without using viruses to insert DNA
Study of prostate cancer in 202 men, whose cancers had spread and were resistant to standard treatment, found that about 17 percent of these cancers belong to a deadlier subtype of metastatic prostate cancer.
UCSF researchers have identified the sequence of genetic changes that transform benign moles to into malignant skin cancer.
UCSF researchers have identified a key biological pathway in human cancer patients that appears to prime the immune system for a successful response to immunotherapy drugs – checkpoint inhibitors.
Researchers identified a protein that cancer cells use as a shield to protect the PI3K pathway against targeted drugs, and showed that blocking this protein allowed previously ineffective therapies to slow cancer cell growth and shrink tumors.
The journey from discovering and developing effective, precise medications to using them correctly and safely in patients is hardly fast and easy. Nor is it a straight shot. Scientists in the UCSF School of Pharmacy are challenging the status quo every step of the way.
UCSF neuroscientist identified the first potential treatment for the brain damage caused by exposure to cosmic rays.
UC San Francisco researchers have discovered a promising new line of attack against lethal, treatment-resistant prostate cancer.
Automated breast-density evaluation was just as accurate in predicting women’s risk of breast cancer, found and not found by mammography, as subjective evaluation done by radiologists.
New study could make it much easier for physicians to use the genetic profile of a patient’s tumor to pick the chemotherapy treatment with the fewest side effects and best chance of success.
A new study finds that a common cancer-causing mutation in a GTPase called Gαs subverts the model for this type of growth switch in cancer.
UCSF scientists uncovered a common genetic driver of aggressive meningiomas, which could help clinicians detect dangerous cancers earlier and lead to new therapies.
Adolescents who smoke e-cigarettes are exposed to significant levels of potentially cancer-causing chemicals also found in tobacco cigarettes, even when the e-cigarettes do not contain nicotine.
New research led by David Solomon, an assistant professor in the Department of Pathology at UCSF, provides much-needed targeted treatment options for patients whose tumors cannot be surgically removed.
A new UCSF study has shown that a cancer-killing (“oncolytic”) virus currently in clinical trials may function as a cancer vaccine.
In older men who survived low-risk cancer and have limited life expectancy, frequent PSA screenings may do more harm than good
Treatment with an investigational androgen receptor inhibitor significantly delayed the development of metastasis in patients with prostate cancer that had become resistant to standard androgen-deprivation therapy.
UCSF scientists have invented a technique that lets them precisely and reversibly disrupt the action of specific cellular proteins at a microscopic scale by making them split apart when illuminated with blue light.
Researchers at UCSF have found a way to attack one of the most common drivers of lung, colorectal, and pancreatic cancer by targeting the proteins it produces on the outside of the cell.
SF CAN is targeting the five most common cancers which collectively account for half of all new cancers in San Francisco.
UCSF: The Campaign is taking on the world’s most complex health challenges, powered by an exceptional community of mavericks, innovators, and advocates. Together we will make the Bay Area and our world healthier for all.
