Drug Targets for Ebola, Dengue, and Zika Viruses Found in Lab Study
Scientists identified key ways Ebola, Dengue, and Zika viruses hijack the body’s cells, and they found at least one potential drug that can disrupt this process in human cells.
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University of California San Francisco
Give to UCSFScientists identified key ways Ebola, Dengue, and Zika viruses hijack the body’s cells, and they found at least one potential drug that can disrupt this process in human cells.
UCSF researchers have devised a CRISPR-based system called SLICE, which will allow scientists to rapidly assess the function of each and every gene in “primary” immune cells.
Using a mouse model, researchers showed that a drug that temporarily suppresses a key component of the brain’s immune system can prevent radiation-associated cognitive decline.
Seven UCSF research subject areas were ranked in the top 10 globally by US News & World Report.
Scientists at UCSF have assembled a searchable database of normal human immunity that researchers can now use as an instant comparison group in studies of the immune system and immune dysfunction.
UCSF’s Max Krummel was a graduate student in the laboratory of Nobel Prize winner James P. Allison, PhD. Now Krummel is leading an ambitious project at UCSF to expand immunology and immunotherapy to understand and potentially treat new diseases.
UCSF is launching the Bakar ImmunoX Initiative, an innovative research program that will promote collaborative, cutting-edge research and data sharing to catalyze discoveries about the central role of the immune system in human health and harness its power to treat a wide range of diseases.
Although CRISPR has made headlines as a powerful system for editing genes, it actually evolved as way for bacteria to defend themselves against infection by viruses.
UCSF researchers discovered fully formed gut and skin cells in the thymus, the organ responsible for training the T cells of the immune system not to attack the body’s own tissues.
UCSF researchers have identified a key biological pathway in human cancer patients that appears to prime the immune system for a successful response to immunotherapy drugs – checkpoint inhibitors.
Silicon Valley is helping researchers like Wendell Lim move basic science breakthroughs into translational applications, making treatments available to patients faster than normally possible.
Treating young children in Sub-Saharan Africa with azithromycin, a safe, inexpensive, and widely used antibiotic, significantly reduced deaths of children under five.
A new study from UCSF shows preterm labor may sometimes happen when the fetal immune system “wakes up” too early and begins to reject the mother, causing the uterus to start contracting.
UCSF scientists have uncovered new mechanisms by which HIV hides in infected cells, resting in a latent state that evades the body’s immune system and preventing antiviral drugs from flushing it out.
The MEI is part of a group of partners that has been awarded a new contract by USAID to support the President’s Malaria Initiative’s Advancing the Progress of Malaria Service Delivery project in 28 countries.
A new UCSF study has shown that a cancer-killing (“oncolytic”) virus currently in clinical trials may function as a cancer vaccine.
A new study shows that an immune signal named interleukin 33 plays a crucial role in allowing the brain to maintain the optimal number of synapses during the development of the central nervous system.
Children with an extremely deadly form of brain cancer might benefit from a new treatment that aims to direct an immune response against a mutant form of a protein found exclusively on cancer cells.
UCSF has ranked in the top 10 for seven specialties in 2017 Best Global Universities rankings released Tuesday by U.S. News & World Report.
UCSF scientists have successfully completed a Phase II clinical trial showing that an FDA-approved antihistamine restores nervous system function in patients with chronic MS.
Newly developed microscopy techniques have allowed UC San Francisco researchers to observe white blood cells in action in unprecedented detail.
Researchers at UCSF have identified specific gut microbes associated with MS in human patients, showing that these microbes take part in regulating immune responses in mouse models of the disease.
Research team led by University of California scientists has used a modified version of the gene-editing technique CRISPR to find enhancers by prompting them into action.
A study headed by UCSF researchers fuels the probiotics debate by finding that there is no clear evidence that a supplement of the “friendly” bacteria strain of lactobacillus prevents eczema.
A virus hiding quietly in the gut may trigger the onset of a severe complication known as graft-versus-host disease (GvHD) in patients who receive bone marrow transplants.
Whether a melanoma patient will better respond to a single immunotherapy drug or two in combination depends on the abundance of certain white blood cells within their tumors, according to a new study.
Immune cells in the brain trigger overeating and weight gain in response to diets rich in fat, according to a new study in mice led by researchers from UCSF and the UW Medical Center.