Bruce Alberts on Why Biomedical Research Needs Rescuing
Bruce Alberts and a group of prominent scientists have begun the Rescuing Biomedical Research initiative to fix what they see as systemic flaws in the current biomedical research enterprise.
University of California San Francisco
Give to UCSFBruce Alberts and a group of prominent scientists have begun the Rescuing Biomedical Research initiative to fix what they see as systemic flaws in the current biomedical research enterprise.
A newly discovered cache of industry documents revealed that the sugar industry began working closely with nutrition scientists in the mid-1960s to single out fat and cholesterol as the dietary causes of coronary heart disease and to downplay evidence that sucrose consumption was also a risk factor.
Gut microbes present in some one-month-old infants predict a three-fold higher risk of developing allergic reactions by age two and asthma by age four.
UCSF's Resource Allocation Program, which offers a single online application process for a wide variety of intramural funding opportunities, is now inviting applications for the fall 2016 cycle.
A new UC San Francisco study challenges the most influential textbook explanation of how the mammalian brain detects when the body is becoming too warm, and how it then orchestrates the myriad responses that animals, including humans, use to lower their temperature.
Two hundred miles above Earth, NASA has conducted the first genome sequencing in space, and researchers at UCSF helped analyze the data sent back from the International Space Station and confirm that the sequencing was a success.
UCSF researchers studying beige fat – a calorie-burning tissue that can help to ward off obesity and diabetes – have discovered a new strategy to cultivate this beneficial blubber.
Early-stage breast cancer patients whose tumors carry genetic markers associated with a low risk of disease recurrence may not need to undergo chemotherapy, suggests a new study that employed a test devised by a UCSF researcher.
An interdisciplinary team of UCSF researchers, led by Xiao Hu, Michele Pelter and Richard Fidler from the UCSF School of Nursing, is working furiously to create and test a “super alarm.”
The ideal interval for breast cancer screening depends on combined assessments of each woman’s breast cancer risk and her breast density, according to a new study led by UCSF and University of Wisconsin researchers.
A new UCSF report on an understudied population – older homeless adults – reveals that adverse childhood experiences have long-lasting effects.
The number of Americans diagnosed with concussions is growing, most significantly in adolescents. UCSF researchers recommend that adolescents be prioritized for ongoing work in concussion education, diagnosis, treatment and prevention.
An international team of researchers has developed a new opioid drug candidate that blocks pain without triggering the dangerous side effects of current prescription painkillers.
A new UCSF-led study concludes that the price of a promising new class of cholesterol-lowering drugs would need to be reduced by up to 70 percent to be cost-effective.
The abundance of a subtype of white blood cells in melanoma tumors can predict whether or not patients will respond to a form of cancer immunotherapy known as checkpoint blockade, according to a new study led by UCSF researchers and physicians.
UC San Francisco’s Clinical and Translational Science Institute (CTSI) has received $85 million over five years from the National Institutes of Health (NIH) to continue to provide training, research support and other services, and to launch new programs aimed at diversifying the patients in research and advancing precision medicine.
A new analysis of nationwide emergency department (ED) records led by UC San Francisco researchers has revealed that black patients seen for back or abdominal pain are roughly half as likely as white patients to be prescribed opioids in the ED or at discharge.
The first results from a large international study of patients taking metformin, the world’s most commonly used type 2 diabetes drug, reveal genetic differences among patients that may explain why some respond much better to the drug than others.
A new study led by UCSF scientists shows that a bacterium commonly found in the human gut is overrepresented in patients with a rare, often disabling autoimmune disease known as neuromyelitis optica.
A new UCSF study shows that specialized brain cells in mice “predict” the hydrating effects of drinking, deactivating long before the liquids imbibed can actually change the composition of the bloodstream.
In a surprising finding, researchers at UC San Francisco have discovered that the prevalence among Americans of chronic kidney disease (CKD), a condition that costs Medicare tens of billions of dollars to treat each year, hasn't increased since the early 2000s.
One minute of exposure to second-hand smoke from marijuana diminishes blood vessel function to the same extent as tobacco, but the harmful cardiovascular effects last three times longer, according to a new study in rats led by UCSF researchers.
With two projects already underway to find new therapies for children with difficult-to-treat cancer and to help doctors diagnose hospitalized patients with acute infections, the California Initiative to Advance Precision Medicine (CIAPM) is announcing a new round of funding open to a wider range of applicants.
Infants who are exclusively breastfed early in life are more likely by age 4 or 5 to have longer telomeres, the protective bits of DNA that cap the ends of chromosomes in cells.
A serious childhood cancer takes advantage of a quality control mechanism that usually protects cells from stress-induced damage to propel tumor growth, according to a new study led by researchers at UC San Francisco and the University of Pittsburgh.
Reducing sugar consumption in obese children, rather than cutting calories or starch, or losing weight, leads to a sharp decline in triglycerides and a key protein called ApoC-III – two features that are associated with heart disease in adulthood.
Zika virus can infect numerous cell types in the human placenta and amniotic sac, according to researchers at UCSF and UC Berkeley who show in a new paper how the virus travels from a pregnant woman to her fetus.
A new UCSF study of top-rated mobile health apps showed that they offer little help to vulnerable patients – those who might benefit the most from these tools.
Using advanced imaging technology that allowed them to spy on interactions among cells in the lymph nodes of living mice, a research team led by UCSF scientists has identified a cell that is a key player in mounting the immune system’s defense against cancer.
Symptoms of infection with the Zika virus in Brazil may be masked by simultaneous infection with other mosquito-spread viruses common in the same region — such as dengue fever and chikungunya viruses — pointing to the need for comprehensive testing, according to a study led by a UCSF expert in DNA-based diagnostics in collaboration with Brazilian researchers.