UCSF Researcher Identifies Risk Genes for ALS
The largest analysis to date of genetic data in ALS has identified two previously unrecognized genetic risks that are significantly associated with the disease.
University of California San Francisco
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Memory-Enhancing Drug Acts as Molecular 'Staple'
UCSF researchers have shown that an experimental brain boosting drug, ISRIB, acts like a molecular staple, pinning together parts of a much larger protein involved in cellular stress.
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New Blood Thinners May Shorten Patients’ Hospital Stays
The use of newer blood-thinners for patients at risk of stroke may lead to two fewer days in the hospital for those who experience complications, with the same survival rate as the older drug warfarin.
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Aggressive Growth of Common Brain Tumors Linked to Single Gene
UCSF scientists uncovered a common genetic driver of aggressive meningiomas, which could help clinicians detect dangerous cancers earlier and lead to new therapies.
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Expert Review Will Strengthen Emerging Digital Technologies
In the absence of rigorous preclinical testing from the FDA, health systems should carefully scrutinize digital tools that interact with electronic health records to recommend patient diagnoses or therapies.
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Once-Mysterious ‘Atacama Skeleton’ Illuminates Genetics of Bone Disease
Ata's appearance can most likely be explained by a handful of rare genetic mutations—some already known, others newly discovered—that are linked to dwarfism and other bone and growth disorders.
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AI is Quicker, More Effective Than Humans in Analyzing Heart Scans
A type of AI known as advanced machine learning can classify essential views from heart ultrasound tests faster, more accurately and with less data than board-certified echocardiographers.
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Smartwatch Effective in Detecting Atrial Fibrillation
Irregular heart impulses that lead to stroke can be detected using a smartwatch with a specially designed application, a finding that could eventually lead to new ways to screen patients for earlier treatment.
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Scientists Discover How Gene Mutation Reduces the Need for Sleep
A new study in mice reveals how a gene mutation seen in human short-sleepers may allow them to survive and thrive on just a few hours of sleep.
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Genomic Analysis Reveals Why Asthma Inhalers Fail Minority Children
The largest-ever whole-genome sequencing study of drug response in minority children has revealed new clues about why the front-line asthma drug albuterol does not work as well for minority children.
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Adding Formula May Not Sway Baby from Breast
A study demonstrated a seemingly contradictory way for newborns losing more weight than most to breastfeed in the longer term: add a little formula for a couple of days.
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Women Cyclists Prone to Common Gynecologic Issues But Not Serious Urinary Dysfunction
Women bicycle riders are more likely to experience urinary tract infections, genital numbness and saddle sores, but not more likely to have serious sexual and urinary symptoms than non-cyclists.
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Childhood Mortality Plummets as Community Health Workers Go Door-to-Door in Urban Mali
Sending community health workers door-to-door to look for sick kids in a rapidly urbanizing area of West Africa, and offering them free care, coincided with a dramatic drop in childhood mortality.
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Low Levels of Vitamin B12 May Worsen Walking, Cognition in Parkinson’s Patients
A study of patients with early Parkinson’s disease found that groups with lower levels of vitamin B12 faced on average a more rapid acceleration of both motor and cognitive symptoms.
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Birth of New Neurons in the Human Hippocampus Ends in Childhood
UCSF scientists have shown that in the human hippocampus neurogenesis declines throughout childhood and is undetectable in adults.
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UCSF Retains Position as Top Public Recipient of NIH Funding
In 2017, UCSF received more biomedical research funding from the National Institutes of Health than any other public institution, continuing a seven-year trend.
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2017 NIH Funding: A Look at the Top-Funded Researchers and Their Work
UCSF received more than $593.9 million in federal funding from the National Institutes of Health in 2017 for research across multiple health-science arenas at the University.
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E-Cigarette Use Exposes Teens to Toxic Chemicals
Adolescents who smoke e-cigarettes are exposed to significant levels of potentially cancer-causing chemicals also found in tobacco cigarettes, even when the e-cigarettes do not contain nicotine.
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HIV Begins to Yield Secrets of How It Hides in Cells
UCSF scientists have uncovered new mechanisms by which HIV hides in infected cells, resting in a latent state that evades the body’s immune system and preventing antiviral drugs from flushing it out.
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Genome Sequencing Uncovers Therapy for Rare Brain Tumor
New research led by David Solomon, an assistant professor in the Department of Pathology at UCSF, provides much-needed targeted treatment options for patients whose tumors cannot be surgically removed.
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USAID Awards Global Malaria Contract to UCSF's Malaria Elimination Initiative and Partners
The MEI is part of a group of partners that has been awarded a new contract by USAID to support the President’s Malaria Initiative’s Advancing the Progress of Malaria Service Delivery project in 28 countries.
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Samsung and UCSF Introduce My BP Lab, a Smartphone App for Blood Pressure and Stress Research
Samsung Electronics Co., Ltd. and UCSF have announced the launch of My BP Lab, a jointly developed smartphone research app to help users monitor their blood pressure and stress levels.
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Smoking E-Cigarettes Daily Doubles Risk of Heart Attacks
Daily use of electronic cigarettes is associated with nearly a doubling of the odds of a heart attack.
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Cognitive Benefits of 'Young Blood' Linked to Brain Protein in Mice
Loss of an enzyme that modifies gene activity to promote brain regeneration may be partly responsible for age-related cognitive decline, according to new research in laboratory mice by UCSF.
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Cancer-Killing Virus Acts by Alerting Immune System
A new UCSF study has shown that a cancer-killing (“oncolytic”) virus currently in clinical trials may function as a cancer vaccine.
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Marijuana Should Be Packaged, Regulated Following Tobacco Control Best Practices
California should take an assertive approach to cannabis labeling, packaging and product formulation, according to a new UCSF study.
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Current PSA Monitoring Ignores Risk to Some Prostate Cancer Survivors
In older men who survived low-risk cancer and have limited life expectancy, frequent PSA screenings may do more harm than good
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Wearables Could Catch Heart Problems That Elude Your Doctor
Office visits offer doctors only a snapshot of chronic conditions. That’s where new mobile health-tracking technology can make a real difference, providing detailed and long-term health data for each patient.
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Apalutamide Delays Progression of Nonmetastatic, Castration-Resistant Prostate Cancer
Treatment with an investigational androgen receptor inhibitor significantly delayed the development of metastasis in patients with prostate cancer that had become resistant to standard androgen-deprivation therapy.
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Creation of New Brain Cells May Be Limited, Mouse Study Shows
Many researchers have long assumed that most stem cells in the body can produce new cells indefinitely, but new research at UCSF shows that this is not the case in the brain.
