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A new study by UCSF researchers raises a red flag against adding antibiotics when growing cells in labs, finding that it can induce unintentional genetic changes in the cells and distort test results.
UCSF neuroscientists answered questions about a molecule that reverses severe memory and learning impairments in mice with traumatic brain injury.
Scientists at UCSF have shown that cellular antennae called cilia, found on fat-forming cells interspersed in muscle, play a key role in this muscle-to-fat transformation.
UCSF scientists used an experimental drug to completely reverse severe learning and memory impairments caused by traumatic brain injury in mice.
Specialized cells in the gut sense potentially noxious chemicals and trigger electrical impulses in nearby nerve fibers, according to a new study led by UCSF scientists.
A new study by UCSF researchers revealed the intriguing possibility that HP1α binds to stretches of DNA and pulls it into droplets that shield the genetic material inside from the molecular machinery of the nucleus that reads and translates the genome.
UCSF researchers have drawn a link between genetic abnormalities in neurodegenerative diseases and the formation of RNA foci, work the scientists said may open avenues to the development of new drug treatments.
In a major advance for fundamental biological research, UCSF scientists have developed a tool capable of illuminating previously inscrutable cellular signaling networks.
Researchers at UCSF and elsewhere are turning to virtual experiments for the initial steps of drug development.
Sharks, rays and skates can hunt for prey hidden in the sandy sea floor by “listening” for faint traces of bioelectricity – they can literally sense their prey’s heart beating.
Researchers at UCSF have developed a new optogenetic tool that can be used to completely eliminate single cells from brain networks in animals. The researchers believe the new tool will enable exquisitely precise experiments to help researchers understand how each cell contributes to the whole.
UCSF researchers have discovered a way to switch off the widely used CRISPR-Cas9 gene-editing system using newly identified anti-CRISPR proteins that are produced by bacterial viruses.
White blood cells called neutrophils race after bacteria at speeds up to a thousand times that of most human cells by moving in a special way. Lillian Fritz-Laylin and Megan Riel-Mehan want to know how that works.
Graduate student Lauren Rodda captured a microscopic mage of a mouse gut, which highlights her work to understand the germinal center, where immune cells compete to be the best at recognizing an invading pathogen.
UCSF has ranked as one of the top 20 universities in the world, according to the 2017 Best Global Universities rankings released Tuesday by U.S. News & World Report.
Postdoctoral scholar Audrey O’Neill captured 16 hours of video as part of her work that aims to understand what molecular steps cause cells to self-segregate.
The National Science Foundation has awarded $24 million over five years for a new ‘blue-sky’ bioengineering center based at UCSF.
UCSF, Stanford and UC Berkeley will join forces in a new biomedical science research center funded by a $600 million commitment from Facebook CEO and founder Mark Zuckerberg and pediatrician Priscilla Chan.
Joe DeRisi, co-director of the new Chan Zuckerberg Biohub at Mission Bay, speaks about his vision for the Biohub and what researchers can look forward to.
Bruce Alberts and a group of prominent scientists have begun the Rescuing Biomedical Research initiative to fix what they see as systemic flaws in the current biomedical research enterprise.
Using advanced imaging technology that allowed them to spy on interactions among cells in the lymph nodes of living mice, a research team led by UCSF scientists has identified a cell that is a key player in mounting the immune system’s defense against cancer.
A previously unidentifiable type of low-grade inflammation may explain why common anti-inflammatory drugs such as aspirin have shown promise against some types of cancer – even when patients don’t display typical signs of inflammation.
Researchers have identified a pair of tarantula toxins that target a previously unknown pain pathway in sensory nerves.
A team of cancer researchers led by scientists at UCSF and Memorial Sloan Kettering Cancer Center in New York have developed a first-of-its-kind hybrid drug with the power to outsmart drug-resistant cancers.
UCSF scientists have created a new class of highly customizable biological sensors that can be used to form “logic gates” inside cells of the immune system, giving these cells the capability to home in on and kill a wide range of cancer cells while preventing them from attacking normal tissue.
UCSF researchers has discovered that single-celled yeast have sensory biases that can be hacked by a carefully engineered illusion, a finding that could be used to develop new approaches to fighting diseases such as cancer.
Scientists at the UNC School of Medicine (UNC) and UCSF have created a general tool to probe the activity of orphan receptors, illuminating their roles in behavior and making them accessible for drug discovery.
A research team led by UCSF scientists has identified a molecular switch capable of converting unhealthy white fat into healthy, energy-burning brown fat in mice.
UCSF Sandler Fellow Joseph Bondy-Denomy studies the native roles of CRISPR and anti-CRISPR proteins in bacteria and phages.
The National Institutes of Health (NIH) has awarded seven grants to UCSF scientists to pursue innovative approaches to major contemporary challenges in biomedical research.