University of California San Francisco
Give to UCSFAfter phages infect bacteria, they construct an impenetrable “safe room” inside of their host, which protects vulnerable phage DNA from antiviral enzymes. This compartment, which resembles a cell nucleus, is the most effective CRISPR shield ever discovered in viruses.
UCSF physician Peter Ganz and colleagues at Colorado-based SomaLogic Inc., are developing what they call “liquid health check” technology – a single blood test capable of painting a detailed portrait of a person’s current health and future disease risks.
The brief surveys evidence from more than 20 studies on the safety of abortion, the harms of denying women abortions when they seek them, and what happens when abortion providers are required to obtain admitting privileges.
UCSF scientists found that an early-life window of immune tolerance available to a normally harmless bacterial species is firmly closed to another, often pathogenic species — one that is a leading cause of drug-resistant skin infections in the U.S. and occasional source of “flesh-eating” necrosis.
Neuroscientists discovered how the listening brain scans speech to break it down into syllables. The findings provide for the first time a neural basis for the fundamental atoms of language and insights into our perception of the rhythmic poetry of speech.
Three in four patients with anorexia nervosa make a partial recovery. But just 21 percent make a full recovery, a milestone that is most likely to signal permanent remission.
Research shows that after cells are subjected to certain stressful treatments, they appear to gain a new “superpower” that allows them to grow twice as fast as normal — a feature the authors call “supergrowth.”
Using standard animal model of Down syndrome, scientists were able to correct the learning and memory deficits associated with the condition with drugs that target the body’s response to cellular stresses.
We commonly think a full stomach is what tells us to stop eating, but it may be that a stretched intestine plays an even bigger role in making us feel sated.
In a breakthrough with important implications for the future of immunotherapy for breast cancer, UCSF scientists have found that blocking the activity of a single enzyme can prevent a common type of breast cancer from spreading to distant organs.
New study reveals that peer reviewers do not take conflicts of interest disclosures into account in their recommendations to journal editors, likely because of an absence of clear guidelines on how conflicts should impact their evaluations.
With a $106 million gift from the Weill Family Foundation, UC Berkeley, UC San Francisco, and the University of Washington have launched the Weill Neurohub to speed the development of new therapies for diseases and disorders that affect the brain and nervous system.
Adam L. Boxer answers questions about the potential of "basket trials" to accelerate drug development for dementia and neurodegenerative disease.
The net clinical benefit of anticoagulants for atrial fibrillation decreases with age.