International Conference Features UCSF Breast Cancer Experts
UCSF breast cancer experts will present new research and clinical findings at the annual San Antonio Breast Cancer Symposium, the largest and most prestigious breast cancer conference.
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Myocarditis in Cancer Patients Is Driven by Specific Immune Cells
Researchers have identified specific immune cells that drive deadly heart inflammation in a small fraction of patients treated with powerful cancer immunotherapy drugs.
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Marijuana and E-cigs Can Harm the Heart Like Traditional Cigarettes
E-cigarettes and marijuana have similar harmful effects on the heart as tobacco cigarettes, opening the door to abnormal heart rhythms, reports a team of researchers at UCSF.
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“CAR Pooling” Screens Identify Most Effective Cancer Immunotherapy Cells
A new method of comparing massive numbers of CAR-T cells can determine which is most effective and long-lasting against cancer.
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Can Gut Microbes Impact Chemotherapy? So Far, the Answer is ‘Yes’
Bacteria in our guts may play a significant role in the metabolism of anti-cancer drugs that are critical for treating colon cancer and other types of cancers.
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UCSF Study Sheds Light on the Reasons Behind Sex Differences in Myocarditis
Immune checkpoint inhibitors (ICIs) used in cancer care can cause myocarditis, a potentially fatal side effect, and it appears that the adverse cardiac effects may disproportionally impact female patients.
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Drug Turns Cancer Gene Into ‘Eat Me’ Flag for Immune System
A new therapy pulls forward a mutated version of the KRAS protein to help the immune system recognize and destroy cancer cells.
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New Study Finds ‘Widespread Exposure’ to Cancer-Causing Chemicals During Pregnancy
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Research Reveals Mechanisms at Work in Progression of Pancreatic Cysts to Pancreatic Cancer
UCSF-led research outlines the comprehensive immune landscape and microbiome of pancreatic cysts as they progress from benign cysts to pancreatic cancer. Their findings could reveal the mechanism of neoplastic progression and provide targets for immunotherapy to inhibit progression or treat invasive disease.
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Pregnant Women Exposed to Cancer-Causing Chemicals in Dishware, Hair Coloring, Plastics, and Pesticides
Pregnant women in the U.S. are being exposed to chemicals like melamine, cyanuric acid, and aromatic amines that can increase the risk of cancer and harm child development, according to a study from researchers at UCSF and Johns Hopkins Bloomberg School of Public Health.
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Giving Immunotherapy Cells Resilience to Pass the ‘Stress Test’
T cells used in immunotherapy treatments can get exhausted and shut down by fighting cancer cells and tumors. Using a CRISPR-based edit on these cells’ genomes, researchers at UCSF and Gladstone Institutes have rendered the therapeutic cells more resilient against tumors.
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Study Reveals for the First Time That Hearing Loss and Tinnitus Is Common in Cancer Survivors
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Hearing Loss and Tinnitus Are Common In Cancer Survivors
A new UCSF study reports for the first time that significant hearing issues often occur among adult survivors of the most common forms of cancer.
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Do Cancer Centers Push Too Many Tests?
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This Clinical Trial Wanted to End Breast Cancer Disparities. But First It Needed To Enroll Black Women
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Screening and Removal of Precancerous Lesions Prevents Anal Cancer
In a groundbreaking finding, a new study led by UCSF found that routine screening for and removal of precancerous anal lesions can significantly reduce the risk of anal cancer, similar to the way cervical cancer is prevented in women.
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3-D Mammography Technique Benefits Some Women, Not All
For many women, breast cancer screening with a three-dimensional imaging technique called digital breast tomosynthesis (DBT) may not offer advantages over digital mammography, but for some it may reduce the chance of an advanced cancer diagnosis, according to a new JAMA study.
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Can You Buy Your Way to Better Health with Detoxing?
Companies claim there’s bad stuff in our homes and bodies, and we should pay to purge it. What’s worth worrying over?
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Amid Global Shortage, Study Shows How to Cut Contrast Dye Use 83%
As a worldwide shortage of contrast dye for medical imaging continues, a new UCSF research letter in JAMA quantified strategies to safely reduce dye use in computed tomography (CT) by up to 83%. CT is the most common use for the dye.
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New Biomarker Classifications May Improve Treatment for High-Risk Breast Cancer Patients
UCSF research scientists and statisticians have developed improved biomarker classifications as part of their research results in the I-SPY 2 trial for high-risk breast cancer patients. The new cancer response subtypes reflect responsiveness to drug treatments and are intended to help clinicians be more precise in how they target therapies.
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UCSF Cancer Specialists to Present Clinical Findings at Major Conference
The latest advances in cancer care and research will be showcased at the annual American Society of Clinical Oncology (ASCO) Annual Meeting, the world’s largest clinical cancer meeting.
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Navigating From the Genome to the Clinic Using ‘Cell Maps’
Nevan Krogan, PhD, director of UCSF’s Quantitative Biosciences Institute, examines in detail the effects of a handful of genes that seem to play an outsize role in a wide array of diseases.
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Genomic Sequencing Is Changing Diagnosis, Treatment for Patients with Brain Cancer
Brain tumor patients survived longer when treated aggressively with surgery, radiation and chemotherapy. Now, a UCSF study underscores the critical role of genomic profiling in diagnosing and grading brain tumors.
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Treating Tough Tumors by Exploiting Their Iron ‘Addiction’
UCSF researchers successfully leveraged an FDA-approved drug to halt growth of tumors driven by mutations in the RAS gene, which are famously difficult to treat and account for about one in four cancer deaths.
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Solving the Mystery of a Stubborn – and Common – Cancer Gene
Mark Moasser, MD, has sorted out why HER2, the protein driving 1 in 5 breast cancers, is so hard to drug. He explains how the findings correct a naive way of envisioning how HER2 is shaped and how it works.
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Immune Cells Leave Fingerprints on Tumors Metastasized to the Brain, Offering Clues to Future Therapies
Using data from over 100,000 malignant and non-malignant cells from 15 human brain metastases, UCSF researchers have revealed two functional archetypes of metastatic cells across 7 different types of brain tumors, each containing both immune and non-immune cell types.
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Sorting Cancers by ‘Immune Archetypes’ May Offer New Approach For Precision Immunotherapies
UCSF researchers found that cancers from different parts of the body are immunologically similar to one another. They described 12 classes of "immune archetypes" to classify cancer tumors, which can provide unique strategies for enhancing patients’ choice of cancer immunotherapies.
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Surgical Procedure Helps Cancer Patients Face Themselves Again
For patients with skin cancer & facial sarcoma, reconstructing the face with skin grafted from the leg may result in poor color match. A new technique pioneered by UCSF surgeons uses pigmented tissue to achieve a better match.
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International Breast Cancer Conference Features UCSF Health Experts
Helen Diller Family Cancer Research Building Experts from UCSF Health will present new research and clinical findings at the annual San Antonio Breast Cancer Symposium, the world’s largest and most
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$6M Gift from Family of Roblox Creator Launches New Initiative to Advance CAR T Therapy
The UCSF initiative aims to increase the effectiveness and availability of chimeric antigen receptor T-cell (CAR T) therapy for lymphoma patients.
