University of California San Francisco
Give to UCSFNew results from an ongoing collaborative effort to slow the spread of COVID-19 shows that the prevalence of a coronavirus lineage, characterized by the L452R substitution and two other mutations in the virus’s spike protein, has significantly increased in recent months.
In a new study, UCSF and Stanford researchers have identified a central switch that appears to control when neural progenitor cells stop multiplying and start differentiating into mature neurons.
UCSF researchers now have an estimate of how many people may have died as a result of pandemic-related unemployment.
UCSF researchers found that mice in which activity of a protein called eIF4E is diminished, either genetically or pharmaceutically, gain only half the weight of other mice, even if all the mice eat a high-fat diet.
The level of trauma the women had experienced in childhood was associated with the age of their epigenetic clocks.
Tissue biologist Sarah Knox has long been fascinated with saliva. Just when she begins to doubt whether her singular passion will lead to real-world impact, an old family friend reaches out to her with a problem only she may be able to solve.
We turned to UCSF scientists to better understand probiotics and the human microbiome they aim to influence.
Many cancer patients might respond better to treatments with the help of a new prognostic indicator based on a distinctive pattern of gene activity within tumor cells.
Susan Acton discovered ACE2 while searching for new cardiovascular drugs. Decades later, she was surprised to see it popping up in the news once COVID took hold.
A new study finds that inherited genetic variation plays a role in who is likely to benefit from checkpoint inhibitors, which release the immune system’s brakes so it can attack cancer.
A new study of autism risk genes by UCSF and UC Berkeley scientists implicates disruption in prenatal neurogenesis – a process in which specialized “progenitor” cells give rise to new brain cells – in the development of autism spectrum disorders.
A new study shows how minority patients are effectively disqualified from receiving the latest cystic fibrosis drugs approved only for people with mutations more common among white patients.
A UCSF team has engineered a tiny antibody capable of neutralizing the coronavirus.
UCSF researchers found that alcohol has an immediate effect on the heart in patients with atrial fibrillation, the most common life-threatening heart-rhythm disorder.
Patients with severe COVID-19 produce antibodies that paradoxically shut down their immune system’s virus-fighting response just when they need it most.
Few would have predicted last January that a pandemic would upend our daily lives. But one grueling year in, UCSF experts have a clearer view of the path ahead.
“It’s too soon to know if this variant will spread more rapidly than others," said Erica Pan, MD, MPH, State Epidemiologist for the California Department of Public Health.
Depression is among the most common psychiatric disorders, affecting as many as 264 million people worldwide and leading to hundreds of thousands of deaths per year. But as many as 30 percent of patients do not respond to standard treatments such as medication or psychotherapy.
Scientists at UCSF have developed ReScan, an innovative new serological test that employs a specialized version of the technique known as phage display.
A mutated version of the novel coronavirus has been making the news for being more contagious. We asked UCSF infectious disease expert Charles Chiu, MD, PhD, how the new variant emerged, whether available vaccines will still work, and what we need to do now.
A team of researchers has identified for the first time the neurons that are among the first victims of Alzheimer’s disease.
A UCSF pediatrician who is researching methods to control the spread of coronavirus shares why she’s optimistic that schools can reopen safely.
UCSF scientists have discovered a new way to control the immune system’s “natural killer” cells, a finding with implications for novel cell therapies and tissue implants that can evade immune rejection.
Researchersare calling for tailored services and support for older adults living alone with memory issues, who are experiencing extreme isolation, and are exposed to misinformation about the virus and barriers to accessing medical care.
A study headed by UCSF and Columbia University highlights the role that frailty plays in this gender gap.