Blood Test May Reduce Risk of Disability in Kids
An experimental blood test that reflects injury to nerve cells from multiple sclerosis (MS) was found to work for children with MS and other neurological conditions, even when they are symptom-free.
University of California San Francisco
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How a Rare Dementia Unleashes Creativity
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How a Rare Dementia Transforms Patients Into Artists
A rare burst of visual creativity is seen occasionally in patients with frontotemporal dementia. A UCSF-led study offers new insights into how this talent develops as key areas of the brain degenerate.
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We Have a Dopamine Problem
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Bay Area Restaurateurs Grapple With Loss of Smell and Taste After Getting COVID-19
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Genetic Variant Identified That May Increase Multiple Sclerosis Severity
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Could What Makes Multiple Sclerosis Worse Lead to a Cure?
A large, collaborative study on multiple sclerosis (MS) severity found that a single gene variant is predictive of much faster neurodegeneration in MS patients.
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You’ll Soon Be Able to Get a Blood Test for Alzheimer’s. Will You Want One?
The advent of cheap, easy-to-use blood tests for Alzheimer’s disease has the potential to revolutionize diagnosis and treatment. But they also raise difficult questions that the field is only beginning to consider.
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Can this Medication Reverse MS? Brain Biomarker Shows It Can
UCSF researchers developed an approach to measure an over-the-counter allergy medication’s effectiveness in repairing brain damage from multiple sclerosis (MS), making it possible to also assess future therapies for the disorder.
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Beating Seizures by Jamming the Cellular Circuitry
UCSF researchers discover how gabapentin interacts with calcium channels, opening doors for more effective treatments in epilepsy and Lupus by influencing channel biogenesis.
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In the Brain, Scientists Find New Clues to Treating Chronic Pain
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Has Science Cracked the Code on Chronic Pain?
In a first, researchers have identified chronic pain pathways in individuals directly from their neural activity, showing promising paths forward for treatment.
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Chemical Exposure May Raise Your Risk for Parkinson’s
Exposure to trichloroethylene (TCE), a chemical found in the air, water, and soil, may increase the risk of Parkinson's disease by 70%, according to a UCSF study. TCE is commonly used today as a degreasing solvent.
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Scientists Discover a Deadly Brain Cancer’s Hidden Weakness
UCSF scientists have found that brain cancer glioblastoma can cause cognitive decline by affecting neural connections, but the epilepsy drug gabapentin shows promise in blocking this activity, offering hope for new treatments.
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Sleep Phase Can Reduce Anxiety in People with PTSD
Sleep spindles, bursts of brain activity during NREM2 sleep, may regulate anxiety in PTSD, challenging recent studies. Non-invasive therapies could provide relief, such as prescription drugs or electrical brain stimulation. Sleep hygiene is also recommended to maximize the benefit of spindles after a stressful episode.
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Overwhelmed? Your Astrocytes Can Help with That
A newly discovered brain circuit recruits brain cells called astrocytes to calm overactive neurons to produce a calming and relaxing effect.
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Thermo Fisher Scientific Opens Cell Therapy Facility at UCSF to Accelerate Development of Breakthrough Therapies
Thermo Fisher Scientific Inc. and UCSF will accelerate advanced cell therapies for difficult to treat conditions like cancer from a new manufacturing facility.
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UCSF Neurologist Celebrated for Innovative Epilepsy Research
Jon Kleen is named the 2023 Dreifuss-Penry Epilepsy Award recipient by the American Academy of Neurology (AAN). He is honored for his contributions to epilepsy treatment.
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How Do We Smell? First 3D Structure of Human Odor Receptor Offers Clues
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Making Sense of Scents
In a first, UCSF scientists created a molecular-level, 3D picture of how an odor molecule activates a human odorant receptor.
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How a Consistent Sleep Schedule Might Protect Your Heart
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Can a Leading Laboratory Unlock the Cause of Gastrointestinal Disease?
Faranak Fattahi’s lab is a national leader in growing stem cells to model peripheral nerves, focusing on gastrointestinal diseases.
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Do Sleep Medications Increase Your Chances of Dementia?
Sleep medications may increase risk of dementia for white people, though the type and amount of medication may also explain the higher probability.
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Trip Therapy
Could psychedelics become mainstream medicines?
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Aggressive Surgery Increases Survival with Low-Grade Brain Tumors
Resecting brain tumors called gliomas as much as possible soon after diagnosis offers a distinct survival advantage when looking at the disease trajectory 10 years later, find UCSF researchers.
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30 Years On, Are We Winning the Fight Against Alzheimer’s?
UCSF experts discuss the current state of Alzheimer’s treatments and future therapies that may slow progression of the disease.
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During Sleep, Brain Regions Synchronize to Create Motor Memory
While we sleep, our brains process our daily actions to create motor memory, which makes physical acts such as throwing a basketball subconscious.
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Top Dementia Scientists Present Key Findings, Initiatives
UCSF Experts Present Research at the Annual Clinical Trials on Alzheimer’s Disease (CTAD) Conference in San Francisco.
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Parkinson’s Patients and Researchers Search for Exercise ‘Prescription’
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Down Syndrome, Like Alzheimer’s, Is a Double-Prion Disorder
The brains of people with Down syndrome develop the same neurodegenerative tangles and plaques associated with Alzheimer’s disease and frequently demonstrate signs of the neurodegenerative disorder in their forties or fifties. A new study shows that these tangles and plaques are driven by the same amyloid beta (Aß) and tau prions as Alzheimer’s disease.
