University of California San Francisco
Give to UCSF<p>Scientists are making great strides in figuring out how the human brain develops, which are leading to novel ideas about the causes of a range of brain disorders, and are raising hopes for the regeneration of tissue that is lost in diseases such as Alzheimer’s. </p>
Scientists at UCSF have pinpointed a reason older adults have a harder time multitasking than younger adults: they have more difficulty switching between tasks at the level of brain networks.
Parkinson’s disease researcher Robert Nussbaum, a human geneticist and neuroscientist at UCSF, has been named to receive the prestigious Klaus Joachim Zülch Neuroscience Prize for 2011.
For patients with glioma, the most common primary brain tumor, new findings may explain why current therapies fail to eradicate the cancer. A UCSF-led team of scientists has identified for the first time that progenitor rather than neural stem cells underly a type of glioma called oligodendroglioma.
UCSF Nobel laureate Stanley Prusiner, MD, and colleagues have called for Congress to more than quadruple annual federal funding for Alzheimer’s research, saying that with a dedicated effort, there is a chance for a breakthrough against the disease by 2020.
UCSF scientists have received two grants from the California Institute for Regenerative Medicine to refine their human embryonic stem cell-based strategies for treating neurological diseases and liver failure.
UCSF Nobel laureate Stanley B. Prusiner, professor of neurology and director of the Institute for Neurodegenerative Diseases, today (Oct. 15, 2010) was named to receive the National Medal of Science, the nation’s highest honor for science and technology.
Synuclein is a protein that can cause Parkinson’s disease, although it is not clear how. UCSF researcher Robert Edwards, MD, now has discovered that synuclein can affect signal transmission between nerve cells long before disease symptoms arise.
In neurodegenerative diseases, clumps of insoluble proteins appear in patients’ brains. These aggregates contain proteins that are unique to each disease, such as amyloid beta in Alzheimer’s disease, but they are intertwined with small amounts of many other insoluble proteins that are normally present in a soluble form in healthy young individuals.
A commercial brain fitness program has been shown to improve memory in older adults, at least in the period soon after training. The findings are the first to show that practicing simple visual tasks can improve the accuracy of short-term, or “working” visual memory.
The Veterans Health Research Institute or NCIRE will present “The Brain at War: Neurocognitive Consequences of Combat” today (June 17).
UCSF researchers have created the first transgenic mouse to display the earliest signs of Parkinson’s disease using the genetic mutation that is known to accompany human forms of the disease.
A UCSF-led study examining the impact of statins on the progression of multiple sclerosis found a lower incidence of new brain lesions in patients taking the cholesterol-lowering drug in the early stages of the disease as compared to a placebo.
A new report by the Institute of Medicine has found that military service in the Persian Gulf War is a cause of post-traumatic stress disorder in some veterans.
A specific region of the hippocampus, a brain structure that is essential to memory, is significantly smaller in veterans with post-traumatic stress disorder than in those without the condition, according to a study by researchers at the San Francisco VA Medical Center and UCSF.
Low vitamin D blood levels are associated with a significantly higher risk of relapse attacks in patients with multiple sclerosis (MS) who develop the disease during childhood, according to a study conducted by researchers from UCSF.
Stanley B. Prusiner, MD, 55, today was named to receive the 1997 Nobel Prize in Physiology or Medicine for discovering and characterizing an entirely new class of proteins, called prions, which cause several rare and fatal neurodegenerative diseases.