Looking Beyond DNA to See Cancer with New Clarity
Researchers at UCSF and UC San Diego have mapped out how hundreds of mutations involved in two types of cancer affect the activity of proteins that are the ultimate actors behind the disease.
![microscopic images of breast cancer cells](/sites/default/files/styles/news_card__image/public/2021-09/Breast-cancer-cells-NIH.jpg)
University of California San Francisco
Give to UCSFResearchers at UCSF and UC San Diego have mapped out how hundreds of mutations involved in two types of cancer affect the activity of proteins that are the ultimate actors behind the disease.
Researchers at UCSF have gained insight into how cancer cells proliferate despite a myriad of stresses.
What kills most people who die from cancer is not the initial tumor. It’s the intolerable disease burden on the body that arises when tumor cells continually expand their numbers after spreading to different organs.
A new, $9 million grant from the National Cancer Institute to increase ethnic diversity will help the study work toward a goal of enrolling 100,000 or more women overall.
A new model of the causes of breast cancer, created by a team led by researchers at UCSF, Genentech and Stanford University, is designed to capture the complex interrelationships between dozens of primary and secondary breast cancer causes and stimulate further research.
In a breakthrough with important implications for the future of immunotherapy for breast cancer, UCSF scientists have found that blocking the activity of a single enzyme can prevent a common type of breast cancer from spreading to distant organs.
A new web tool spells out for the first time the exposures that more than 6.5 million working women in California face that could increase their risk for breast cancer, including industrial solvents, antimicrobials and phthalates.
UC San Francisco scientists have designed a large-scale screen that efficiently identifies drugs that are potent cancer-killers when combined, but only weakly effective when used alone. Using this
UCSF demonstrates that cancer is a clever engineer, capable of constructing entirely new disease-promoting networks out of raw materials readily available in the cell.
UCSF researchers found that 58 percent of women who resided in a nursing home for more than 90 days before breast cancer surgery experienced significant functional decline one year after surgery.
Follow-up imaging for women with non-metastatic breast cancer varies widely across the country, according to a new study led by researchers at UCSF.
Researchers identified a protein that cancer cells use as a shield to protect the PI3K pathway against targeted drugs, and showed that blocking this protein allowed previously ineffective therapies to slow cancer cell growth and shrink tumors.
Automated breast-density evaluation was just as accurate in predicting women’s risk of breast cancer, found and not found by mammography, as subjective evaluation done by radiologists.
New study could make it much easier for physicians to use the genetic profile of a patient’s tumor to pick the chemotherapy treatment with the fewest side effects and best chance of success.
More and more, the promise of EHRs transforming data into knowledge is beginning to bear fruit.
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Women who receive a breast cancer diagnosis while they are still young enough to bear children can take time to freeze their eggs and embryos without fear of delaying their cancer treatment.
A molecular test can pinpoint which patients will have a very low risk of death from breast cancer even 20 years after diagnosis and tumor removal, according to a new clinical study led by UCSF in collaboration with colleagues in Sweden.
Asian-American women are more likely to experience delays in follow-up treatment after an abnormal mammogram compared to white women, according to new UCSF research.
Cancer specialists from UCSF will present new findings at the annual meeting of the American Society of Clinical Oncology (ASCO), the world’s largest clinical cancer research meeting.
Scalp cooling can lessen some chemotherapy-induced hair loss – one of the most devastating hallmarks of cancer – in certain breast cancer patients, according to a new multicenter study from UCSF, Weill Cornell Medicine and three other medical centers.
Women whose breasts are composed largely of glandular tissue, rather than fat, have an amplified risk of breast cancer, which exceeds the impact of other widely known risks on a population level.
Stories about sensory processing disorder, videos about “zombie” cancer cells, and news about the effects of caffeine and alcohol on the heart were among the topics that most engaged our readers in 2016.
A team of researchers led by UCSF scientists has identified a new drug target for triple-negative breast cancer.
Early-stage breast cancer patients whose tumors carry genetic markers associated with a low risk of disease recurrence may not need to undergo chemotherapy, suggests a new study that employed a test devised by a UCSF researcher.
The ideal interval for breast cancer screening depends on combined assessments of each woman’s breast cancer risk and her breast density, according to a new study led by UCSF and University of Wisconsin researchers.
A previously unidentifiable type of low-grade inflammation may explain why common anti-inflammatory drugs such as aspirin have shown promise against some types of cancer – even when patients don’t display typical signs of inflammation.
The most intractable common form of breast cancer might in most cases be treatable by drugs that target fat metabolism, according to UCSF researchers.