48 UCSF Researchers Are Honored for Their High-Impact Science
Nearly 50 UCSF researchers have been named to Clarivate’s list of most influential scientists for 2024.
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Engineered Receptors Help the Immune System Home in on Cancer
UCSF researchers develop customizable SNIPR sensors that activate engineered cells only near tumors, promising precise cancer therapies with minimal side effects.
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Astronauts to Grow Livers in Space, Where Microgravity Might Help Them Thrive
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UCSF Receives Major Award to Speed Drug Development with AI
With the help of up to $30M in funding, researchers led by UCSF’s James Fraser, PhD, will use AI to map drug “anti-targets,” aiming to speed up drug development and reduce costs.
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Precision Breast Cancer Trial Shows Improved Treatment by Tumor Subtype
Breast cancer is the second leading cause of cancer deaths in the U.S. and worldwide, pointing to the continuing need to improve treatment strategies and therapies that better patient survival and
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A Molecular Signal Works its Magic from Inside a Straitjacket
Powerful electron microscopy and 3D imaging leads scientists to a new discovery showing how the TGF-Beta signaling protein is able to move much more freely than previously thought.
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Cracking Codes in Cellular Communication
Aashish Manglik delivered the 29th annual Byers Award Lecture titled “Signal Reception: Cracking Codes in Cellular Communication.”
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Healthy Diet with Less Sugar Is Linked to Younger Biological Age
Added sugar in diet can speed up epigenetic aging, while a sustained, healthy diet with can slow it down and possibly reverse biological aging.
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Scientists Discover a New Hormone that Can Build Strong Bones
A newly discovered hormone explains why females can maintain bone density during lactation, when calcium is stripped away to make milk. This discovery could one day have applications to treating fractures, osteoporosis, and other bone diseases.
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How the Cell Cycle Orchestra Plays an Unexpected New Tune
Multiciliated cells, cells with hundreds of hair-like structures that move called cilia, keep things like mucus in the lungs and cerebrospinal fluid in the brain flowing in the right direction.
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Can a New Drug Candidate Cure Pancreatic Cancer?
A new drug candidate permanently modifies a wily cancer-causing mutation, paving the way for making pancreatic cancer treatable, or perhaps even curable.
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Better Way to Deliver Fetal Therapy for Serious Genetic Disorders
Delivering medicine through amniotic fluid is as effective as delivering it to the fetal brain via cerebrospinal fluid to treat serious disordrs such as Angelman syndrome.
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How AI Can Help Spot Early Risk Factors for Alzheimer’s Disease
UCSF scientists found a way to predict Alzheimer’s disease up to seven years before symptoms appear by analyzing patient records with machine learning. Conditions that most influenced prediction of Alzheimer’s were high cholesterol and, for women, osteoporosis.
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Over 30 UCSF Scientists Honored for Highest Impact in Their Fields
Thirty-two UCSF scientists are among the most influential individuals in their respective fields, according to the most recent analysis of research citations by the science and intellectual property company, Clarivate.
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Can What Works to Treat Cancer Work for Diabetes?
UCSF researchers are working across disease specialties. Diabetes researchers are looking at how oncologists use CAR T-cell therapy to reprogram a person’s immune system to attack cancer cells, for example. They hope to similarly reprogram the immune system to fight diabetes.
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How a Human Smell Receptor Works Is Finally Revealed
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The Cancer Breakthrough Boom
Engineered immune cells. Supercharged scans. Drug implants. Gene manipulators. Blood biopsies. Read how these breakthroughs are transforming cancer care.
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Two UCSF Researchers Win Pew Awards for Biomedical Science
Two UCSF scientists – James Gardner, MD, PhD, and Rebeca de Pavia Fróes Rocha, PhD – have received Pew awards for their work in immunology as part of a program that supports promising early-career investigators.
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UCSF Health Cancer Experts Featured at Premier Cancer Meeting
Oncology specialists from around the globe will gather for the American Society of Clinical Oncology (ASCO) Annual Meeting to discuss the latest cancer therapies, technologies, research and education.
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Beating Seizures by Jamming the Cellular Circuitry
UCSF researchers discover how gabapentin interacts with calcium channels, opening doors for more effective treatments in epilepsy and Lupus by influencing channel biogenesis.
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Ibogaine Inspires New Treatments for Addiction and Depression
A traditional African psychedelic plant medicine called ibogaine is the blueprint for two new drug candidates that could treat addiction and depression.
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Making Sense of Scents
In a first, UCSF scientists created a molecular-level, 3D picture of how an odor molecule activates a human odorant receptor.
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What Enzymes Can Tell Us About Human Health and Global Warming
Because proteins can adapt to extremes, Margaux Pinney, PhD, believes they can show how living organisms might adapt to climate change.
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What We Were Taught About RNA in High School is Only Half the Picture
Vissers’ work on RNA tags helped found the field of epitranscriptomics, the study of how chemical marks on RNA, rather than their sequence alone, dictate the function of the molecules.
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Can a Leading Laboratory Unlock the Cause of Gastrointestinal Disease?
Faranak Fattahi’s lab is a national leader in growing stem cells to model peripheral nerves, focusing on gastrointestinal diseases.
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Can We Turn Back Time on Age-Related Diseases?
Emily Goldberg's lab studies what happens during aging to a particular set of immune cells: those embedded in fat tissue. She hypothesizes that changes to these cells during aging could be key to age-related inflammation.
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The Omicron Effect: Can We Predict the Next Viral Killer?
Angela Phillips, PhD, leads research that could help predict future viruses like COVID and the antibodies we might use to treat them.
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Why Stem Cell Therapy Might Not Work for Older Patients
Leanne Jones, PhD, is at the forefront of studying how stem cells are influenced by their surrounding environment and directed to differentiate into one type of cell or another – research that’s critical for stem cell therapies to be successful.
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‘Bacteria Whisperer’ Aims for New Heights After Winning Top Science Award
Shaeri Mukherjee, PhD, has won the Bowes Biomedical Investigator award, which will provide funding to further her work using bacterial pathogens to identify basic processes inside human cells.
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After a Decade, CRISPR Gene Editing Is a ‘Revolution in Progress.’ What Does the Future Hold?