Could Brain Aging Be Mom’s Fault?
Researchers found that female mice using only maternal X chromosomes showed faster cognitive decline, which could help explain the variation in brain aging between the sexes
University of California San Francisco
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Genes That Grow a Healthy Brain Could Fuel Adult Glioblastoma
A new study paints one of the most detailed pictures of human brain development to date, opening the door to new tests and therapies, including for brain disorders such as autism.
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The Future of Neuroscience: Building a Silicon Brain
A digital twin of a human mind? It isn’t science fiction.
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On the Origin of Diseases
Insights from human evolution could change how we understand and treat illness.
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The Surprising Effect of Stress on Your Brain’s Reward System
UCSF scientists are uncovering the brain mechanisms behind resilience to stress and exploring new, non-invasive treatments for depression through groundbreaking research in mice.
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48 UCSF Researchers Are Honored for Their High-Impact Science
Nearly 50 UCSF researchers have been named to Clarivate’s list of most influential scientists for 2024.
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This AI Tool Helps Neurosurgeons Find Sneaky Cancer Cells
An AI-based diagnostic system reveals cancerous tissue that may not otherwise be visible during brain tumor surgery. This enables neurosurgeons to remove it while the patient is still under anesthesia – or treat it afterwards with targeted therapies.
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Artificial Receptors Could Help Us Solve the Puzzle of Olfaction
Scientists from Duke, UCSF, and City of Hope used cryo-EM to reveal how our noses detect a wide range of odors, offering insights into olfaction.
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Poor Sleep in Midlife Is Linked to Faster Brain Atrophy
Poor sleep in midlife, like difficulty falling asleep or waking early, may accelerate brain atrophy linked to dementia, a UCSF study finds.
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UCSF Benioff Children’s Hospitals Tie for Best in Northern California in 2024-2025
UCSF Benioff Children’s Hospitals have tied as the best hospitals in Northern California in the 2024-2025 U.S. News & World Report Best Children’s Hospitals list.
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Research Points a Way to Modulate Scarring in Spinal Cord Injury
David Julius and Wendy Yue have discovered a natural mechanism that could help reduce scarring after a spinal cord injury.
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New Hope for Progressive Supranuclear Palsy with Innovative Trial
A clinical trial that will test three drugs concurrently, and could include more, represents new hope for patients with progressive supranuclear palsy (PSP), an incurable neurodegenerative disorder that usually kills within seven years after symptoms start.
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New Study: Can Your Phone and AI Track Parkinson’s Progression?
A new video-based symptom assessment system for Parkinson’s Disease that is enabled by machine learning represents a potential solution to the challenge of assessing Parkinson’s Disease progression in a quantifiable way.
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A Personalized Brain Pacemaker for Parkinson’s
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New Parkinson’s Treatment Helps Former Pro Keep Skateboarding
An experimental adaptive deep brain stimulation (aDBS) device had tremendous success in a trial that helped a Parkinson’s patient, who is a former skateboarding professional, resume skating and mentoring San Francisco youth.
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Could This New Drug Turn Back the Clock on Multiple Sclerosis?
Scientists at UCSF and Contineum Therapeutics have developed a drug that spurs the body to replace the protective insulation around nerve cells, myelin, that is lost in multiple sclerosis. If it works in people, it could be a way to reverse the damage caused by the disease.
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Forecasting May Help People with Epilepsy Predict Their Seizures
A team of epilepsy specialists at UC San Francisco has developed a method to predict 24-hour seizure risk. The discovery, which may be scalable to large numbers of patients, could help to improve the
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Scientists Discover a New Hormone that Can Build Strong Bones
A newly discovered hormone explains why females can maintain bone density during lactation, when calcium is stripped away to make milk. This discovery could one day have applications to treating fractures, osteoporosis, and other bone diseases.
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Breakthrough: How AI Uses Videos to Gauge Parkinson's Severity
Despite recent advancements in the treatment of Parkinson’s Disease, it remains a challenge to accurately measure the progression of symptoms like tremors, stiffness and slowing of movement for this
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Scientists May Have Found How to Diagnose Elusive Neuro Disorder
Scientists have identified the biomarkers in progressive supranuclear palsy, a type of frontotemporal dementia, the most common dementia affecting people under 60.
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Poor Health, Stress in 20s Takes Toll in 40s With Lower Cognition
A study linked chronic inflammation in early adulthood to loss of cognitive skills in midlife. Chronic inflammation is caused by obesity, smoking, and poor health. Those with higher levels of inflammation were twice as likely to have poor cognitive performance than those with low inflammation.
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UCSF Scientists Win Pew Awards for Cancer and Neuroscience Research
Three UC San Francisco scientists have received 2024 Pew awards to fund their research in neuroscience and cancer: cognitive scientist Vijay Mohan K Namboodiri, PhD; bioengineer Justin Eyquem, PhD; and postodctoral student Jovanka Gencel-Augusto, PhD.
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How a Brain Implant and AI Gave a Woman with Paralysis Her Voice Back
UCSF scientists made international headlines when they developed a brain-computer interface that allowed a stroke survivor to speak for the first time in 18 years. Find this award-winning video, which has been viewed by millions, on UCSF’s YouTube channel.
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How a Team of Brain Detectives Is Cracking the Hardest Cases
A new diagnostic clinic for mysterious nervous-system disorders is giving patients answers they can’t find anywhere else.
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A Cure for Multiple Sclerosis? Scientists Say Within Our Lifetime
A generation ago, a diagnosis of multiple sclerosis was a guarantee of a debilitating disease that would leave the patient wheelchair bound, and worse. Follow UCSF’s role in what some call the golden age of MS research and care.
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A Drug to Slow Alzheimer’s Is Finally Available. How Are Patients Faring?
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Degraded Synapses in the Retina Can Predict the Severity of MS
The disabling effects of multiple sclerosis may be caused in part by damaged connections between neurons, and this can be seen in the eye, UC San Francisco researchers have found. They showed that
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When Depression Meds Don’t Work, This May Help You Turn the Corner
Transcranial magnetic stimulation (TMS) is a noninvasive in-office procedure. Brief magnetic pulses to the brain induces electrical currents that stimulate nerve cells in specific areas of the brain, providing symptom relief for patients with depression and OCD.
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Signs of Multiple Sclerosis Show Up in Blood Years Before Symptoms Appear
UCSF scientists have found a set of autoantibodies that emerge in some MS patients years before symptoms.
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What Makes You Cough When Something Goes Down the Wrong Pipe?
When a mouthful of water goes down the wrong pipe – heading toward a healthy person’s lungs instead of their gut – they start coughing uncontrollably. That’s because their upper airway senses the
