CryoEM Study Captures Opioid Signaling in the Act
Scientists have used ultra-high-resolution cryo–electron microscopy to capture the most detailed portrait ever of an opioid drug triggering the biochemical signaling cascade that gives it its power.
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University of California San Francisco
Give to UCSFScientists have used ultra-high-resolution cryo–electron microscopy to capture the most detailed portrait ever of an opioid drug triggering the biochemical signaling cascade that gives it its power.
Forty percent of deaths attributed to cardiac arrest are not sudden or unexpected, and nearly half of the remainder are not arrhythmic – the only situation in which CPR and defibrillators are effective.
People with severe mental illness are more than twice as likely to have Type 2 diabetes, with even higher risks among patients who are African American or Hispanic, according to a new study led by UCSF.
A staggering 64,000 people in the United States died in 2016 from drug overdoses – and a study led by UCSF’s Daniel Ciccarone is aiming to get at the heart of of the problem, including by interviewing opioid users.
The journey from discovering and developing effective, precise medications to using them correctly and safely in patients is hardly fast and easy. Nor is it a straight shot. Scientists in the UCSF School of Pharmacy are challenging the status quo every step of the way.
Mayor Mark Farrell announced $4.2 million in additional funds for HIV/AIDS programs in San Francisco.
Infectious disease expert Charles Chiu explains the rise in Lyme disease cases, better diagnostic tests on the horizon and what you need to know to protect yourself from infection.
More than 100 members of the malaria research community in the Bay Area gathered to celebrate World Malaria Day on April 25 at Zuckerberg San Francisco General Hospital.
All of Us is an unprecedented effort to gather genetic, biological, environmental, health and lifestyle data from 1 million or more volunteer participants living in the U.S., officially opens for enrollment May 6.
Treating young children in Sub-Saharan Africa with azithromycin, a safe, inexpensive, and widely used antibiotic, significantly reduced deaths of children under five.
A newly launched Lancet Commission on Malaria Eradication will convene experts from around the world to develop the first-ever roadmap to eradicate malaria.
Mike Reid, who has worked around the globe providing treatment for serious infectious diseases, is part of a growing effort to eliminate tuberculosis worldwide.
UCSF’s School of Medicine placed in the top five nationally in this year’s U.S. News & World Report survey of best graduate and professional schools. UCSF’s biomedical science PhD programs were among the top 10, and the School of Nursing was also highly ranked.
Sending community health workers door-to-door to look for sick kids in a rapidly urbanizing area of West Africa, and offering them free care, coincided with a dramatic drop in childhood mortality.
UCSF scientists have uncovered new mechanisms by which HIV hides in infected cells, resting in a latent state that evades the body’s immune system and preventing antiviral drugs from flushing it out.
The MEI is part of a group of partners that has been awarded a new contract by USAID to support the President’s Malaria Initiative’s Advancing the Progress of Malaria Service Delivery project in 28 countries.
A new UCSF study has shown that a cancer-killing (“oncolytic”) virus currently in clinical trials may function as a cancer vaccine.
In older men who survived low-risk cancer and have limited life expectancy, frequent PSA screenings may do more harm than good
An international team of researchers has shown that two different compounds, can safely and effectively be added to treatment regimens to block transmission of the most common form of malaria in Africa.
UCSF’s Charles Chiu, MD, PhD, an expert in infectious diseases, answered some questions about this year’s flu season.
Much of San Francisco’s progress in fighting new HIV infections can likely be contributed to Getting to Zero – a citywide collaboration to end HIV transmission that was co-founded by UCSF.
Three UC San Francisco researchers have been selected as fellows of the American Association for the Advancement of Science (AAAS), the world’s largest general scientific society and publisher of Science and three other peer-reviewed journals.
UCSF researchers are leading several initiatives that aim to see how dozens of seemingly unrelated genes and proteins involved in a disease are in fact all part the same interconnected biological pathway.
Joe DeRisi, PhD, a master detective of infectious diseases, stumbled on a clue to cracking the decades-long search for the place – or creature – where the Ebola virus hides between deadly outbreaks.
Global Health Sciences is celebrating the 10th anniversary of the Global Health Group, and it has a long list of accomplishments to claim from that time.
UCSF Health Informatics team has used electronic health records to track down a source of a common hospital-acquired infection.
A new UC San Francisco–led study shows that failure to follow this basic principle of population science can profoundly skew the results of brain imaging studies.
Pregnant women who are diagnosed with sleep disorders such as sleep apnea and insomnia appear to be at risk of delivering their babies before reaching full term.
UCSF School of Medicine Dean Talmadge E. King, Jr. announced the appointment of Kirsten Bibbins-Domingo as the new chair of the Department of Epidemiology and Biostatistics and the inaugural vice dean for Population Health and Health Equity.