Alzheimer’s Disease is a ‘Double-Prion Disorder,’ Study Shows
Two proteins central to the pathology of Alzheimer’s disease act as prions – spreading through tissue like an infection by forcing normal proteins to adopt the same misfolded shape.
![Science image of cells.](/sites/default/files/styles/news_card__image/public/2019-05/ab42-cells-uninfected-infectedwith-amyloid-beta-prions.png)
University of California San Francisco
Give to UCSFTwo proteins central to the pathology of Alzheimer’s disease act as prions – spreading through tissue like an infection by forcing normal proteins to adopt the same misfolded shape.
Made possible by a $30 million gift from Marc and Lynne Benioff, UCSF announced the launch of the UCSF Benioff Homelessness and Housing Initiative, a new center that will research and identify evidence-based solutions to prevent and end homelessness.
UCSF research has identified a particular group of nerve cells in the brain that play an important role in anxiety’s influence over behavior.
The technology could one day restore the voices of people who have lost the ability to speak due to paralysis and other forms of neurological damage.
In the largest analysis to date of narrative medical school evaluations, researchers at UC San Francisco and Brown University have found significant differences in how female and underrepresented
UC San Francisco is collaborating with the nonprofit Lazarex Cancer Foundation on a three-year study to identify ways to improve cancer clinical trial participation among medically underserved populations, including low-income individuals and racial and ethnic minorities.
Reducing smoking, and its associated health effects, among Medicaid recipients in each state by just 1 percent would result in $2.6 billion in total Medicaid savings the following year, according to
While organ transplant recipients receive continual care as the end-stage treatment to their condition, attention also should be given to living donors, who can suffer from hypertension, diabetes and
UC San Francisco scientists have designed a large-scale screen that efficiently identifies drugs that are potent cancer-killers when combined, but only weakly effective when used alone. Using this
At least six states with high opioid abuse rates also have strong work restrictions that hinder nurse practitioners in prescribing medication that can help treat the problem.
Image courtesy of the National Cancer Institute Immunotherapy drugs known as checkpoint inhibitors have revolutionized cancer treatment: many patients with malignancies that until recently would
Amyloid positive PET scan. A first-of-its-kind national study has found that a form of brain imaging that detects Alzheimer’s-related “plaques” significantly influenced clinical management of
New UCSF study may have answered how your brain knows when you’ve had enough water.
A delicate operation that involved placing a gene into the brain was found to reduce the severity of motor symptoms in patients with moderately advanced Parkinson’s disease.
More than 150 people have signed up to shave their heads at UCSF Benioff Children’s Hospital Oakland on March 16, to support the 12th annual Brave the Shave fundraiser for pediatric cancer research.
Tobacco conglomerates that used colors, flavors and marketing techniques to entice children as future smokers transferred these same strategies to sweetened beverages when they bought food and drinks companies.
Properly caring for the skin with a moisturizing cream may lower inflammation levels and potentially prevent age-related diseases, according to a new clinical pilot study.
UCSF was the only medical school to be ranked in the top five in the nation in both research and primary care, the categories the magazine uses to assess medical education.
After a heart attack, the heart tissue is often irreparably damaged. According to UCSF study, the issue may date back to our earliest mammalian ancestors.
UCSF researchers developed a strategy for targeting a key molecule implicated in Parkinson’s disease, opening up a potential new treatment strategy for the currently incurable movement disorder.
Researchers at UCSF say Google Translate is trustworthy when translating written medical advice, but there are some caveats.
UCSF researchers have created a proof-of-concept method for ensuring the integrity of clinical trials data with blockchain.
A UCSF study of human and mouse pancreatic tissue suggests a new origin story for type 1 diabetes.
A program offering group support, acupuncture, mindfulness, massage and gentle exercise may help prevent patients on prescription opioids from spiraling down to drug misuse, overdose and death.
UCSF scientists have used the CRISPR-Cas9 gene-editing system to create the first pluripotent stem cells that are functionally “invisible” to the immune system.
A personal survey of patients with AF has found that the majority of triggers for the condition are easily modifiable lifestyle choices, including alcohol, caffeine, exercise and lack of sleep.
UCSF Fresno recently received contributions of more than $1 million from two development companies and families known for giving back to the local community.
Scientists at UCSF, in collaboration with colleagues at UNC, have developed the world’s largest virtual pharmacology platform and shown it is capable of identifying extremely powerful new drugs.
UCSF researchers have for the first time transformed human stem cells into mature insulin-producing cells, a major breakthrough in the effort to develop a cure for type 1 (T1) diabetes.