University of California San Francisco
Give to UCSFA UCSF investigator has won an eight-year grant from the National Cancer Institute for a major investigation into anal cancer, a debilitating and sometimes fatal disease largely concentrated among people with HIV.
A team led by UCSF scientists has identified the disruption of a single type of cell – in a particular brain region and at a particular time in brain development – as a significant factor in the emergence of autism.
The protein in cells that most often drives the development of cancers has eluded scientists’ efforts to block it for three decades — until now.
Current anti-obesity treatments include strategies to prevent food energy from being absorbed, such as orlistat, which prevents fat absorption from food.
Precision Medicine Pillar No. 5: Omics Medicine. Molecular biologist Nevan Krogan's work is not only illuminating how genes and proteins function, it's also shedding light on the underlying biology of disease for each person.
Precision Medicine Pillar No. 6: Digital Health. The Center for Digital Health Innovation shepherds the development of digital health innovations created at UCSF and validates the effectiveness of devices from both inside and outside the institution.
Precision Medicine Pillar No. 3: Clinical Discovery. Researchers are taking vast amounts of patient data, often collected through first-ever clinical studies, and putting it into tools like MS Bioscreen that have a direct impact on patient care.
Precision Medicine Pillar No. 4: Computational Health Sciences. Computationally intensive approaches are used to analyze and cross-analyze large but discrete collections of data, such as patient health histories and genetic makeup.
Precision Medicine Pillar No. 2: Basic Discovery. The long path to developing potent new treatments often starts with an observation in the lab that then leads to a question about a fundamental life process.
Precision Medicine Pillar No. 1: Knowledge Network. With an increased ability to harvest information automatically and more powerfully, scientists can find the connections among discoveries that would otherwise go unrecognized.
Researchers at the UCSF-affiliated Gladstone Institutes have discovered how the activation of specific stretches of DNA control the development of uniquely human characteristics.
UCSF scientists were able to arrest, and even reverse, tissue scarring of the liver, kidneys and lungs in mice. The scarring, also known as fibrosis, is a major factor in nearly half of all deaths in developed countries.
When it comes to genes, a UCSF scientist wants to turn conventional wisdom about human and bacterial evolution on its head.
UCSF, a world-renowned center for the treatment of movement disorders, is holding an event to celebrate the program’s recognition by the Bachmann-Strauss Foundation as one of three new Centers of Excellence in the field.
A UCSF graduate program in complex biology led by Joseph DeRisi, PhD, is being lauded for its creativity with a $100,000 gift.
Eleven leading scientists from the California Institute for Quantitative Biosciences (QB3) presented their latest aging research findings and anti-aging strategies at a daylong symposium called “The Science of Staying Younger Longer.”
Barbara Drew is leading research to solve the dangerous problem of alarm fatigue, in which clinicians turn down, turn off or tune out the alarms because they're exhausted by their frequency and false readings.
New research by scientists at UC San Francisco shows that one of the brain’s fundamental self-protection mechanisms depends on coordinated, finely calibrated teamwork among neurons and non-neural cells.
In recent years, studies have reported inconsistent findings regarding whether calcium supplements used to prevent fractures increase the risk of heart attack.
A UCSF-led team of scientists has discovered that a gene mutation found in some bladder cancers is indicative of low-risk tumors that are unlikely to recur or progress after surgery.
Through support from the Catalyst Awards, UCSF researcher Aditi Bhargava is working to develop a method for delivering small-molecules to a specific target group of cells for treatment of pain.
A team of UCSF researchers developing cell-based therapies for acute respiratory distress syndrome benefited from advisors who helped identify gaps in their development plan.
A UCSF opthamologist and bioengineer are collaborating to develop a tiny, flexible, implantable film that's able to deliver conventional medicines and also complex antibody-based drugs to treat eye diseases.
Ruben Rathnasingham, PhD, associate director of Early Translational Research at UCSF's Clinical and Translational Science Institute, is leading the team responsible for LaunchPad. In this Q&A, he discusses the project and how it can benefit researchers.
Teams of scientists at UCSF are collaborating to build upon existing imaging techniques and find new ways to monitor diseases using creative applications of emerging technologies.
The way cells divide to form new cells – to support growth, to repair damaged tissues, or simply to maintain our healthy adult functioning – is controlled in previously unsuspected ways, UCSF researchers have discovered.
Childbirth is not a major contributor to sexual dysfunction in women later in life, according to a new study led by UCSF researchers.