University of California San Francisco
Give to UCSFElderly women who suffer from sleep apnea -- characterized by disrupted breathing and sleep and a reduction in the intake of oxygen -- are about twice as likely to develop dementia in the next five years as those without the condition, according to a multi-center study led by researchers from the University of California, San Francisco.
Scientists have known for years that when vampire bats tear through an animal’s skin with their razor-sharp teeth, their noses guide them to the best spots – where a precise bite will strike a vein and spill forth nourishing blood. But nobody knew exactly how bats knew where to bite – until now.
The completion of a massive genotyping on a large and diverse population marks an unprecedented milestone in population-based genetics research and offers a unique and powerful resource to help answer research questions about aging, health and disease.
Patients diagnosed with traumatic brain injury (TBI) had over twice the risk of developing dementia within seven years after diagnosis compared to those without TBI, in a study of more than 280,000 older veterans conducted by researchers at the San Francisco VA Medical Center and UCSF.
Over half of all Alzheimer’s disease cases could potentially be prevented through lifestyle changes and treatment or prevention of chronic medical conditions, according to a study led by Deborah Barnes, PhD, a mental health researcher at the San Francisco VA Medical Center.
<p>UCSF cognitive neuroscientist Adam Gazzaley has used functional brain imaging and EEG studies to discover that older adults fare worse than younger adults at remembering following distractions. He hopes to improve their performance with cognitive training, using a newly developed video game.</p>
<p>Francis Collins, director of the National Institutes of Health (NIH), describes the scientific goals and functions of the National Center for Advancing Translational Sciences (NCATS), a proposed new entity of the NIH that will strive to reengineer the process of developing drugs, diagnostics, and devices. </p>
<p>As part of his push for the National Institutes of Health to focus more on translational medicine, Director Francis Collins recently toured one of UCSF’s world-class centers of innovation, the California Institute for Quantitative Biosciences (QB3) at Mission Bay.</p>
Researchers at UCSF and in Michigan, North Carolina and Spain have discovered how genetic mutations cause a number of rare human diseases, which include Meckel syndrome, Joubert syndrome and several other disorders.
<p>In the era of prostate cancer screening, mortality rates have fallen 40 percent. The price of that has been over-diagnosis and over-treatment, something the current health care system cannot sustain. One of the major goals of Cooperberg’s research is to develop better risk assessment tools and instruments that can give the patient and doctor more confidence that the patient’s cancer will not progress.</p>
<p>With years of sleep research under her belt, Lee has recently focused on helping parents — especially new and expecting mothers — get enough sleep. From these studies, Lee has found worrisome correlations between sleep deprivation during pregnancy and increased instances of Cesarean operations and length of labor. By educating families about proper sleep hygiene, she hopes to promote healthier home environments for mothers and babies.</p>
<p>By mapping neurons and neuron circuitry during movement, Sabes’ lab hopes to one day to be able to print this information back into the brain. If feasible, such therapy could offer new hope to stroke victims whose brains are unable to recover on their own.</p>